In this paper, new classes of generalized (F,α,ρ, d)-V -type I functions are introduced for differentiable multiobjective programming problems. Based upon these generalized convex functions, sufficient optimality conditions are established. Weak, strong and strict converse duality theorems are also derived for Wolfe and Mond-Weir type multiobjective dual programs.

Relative to a general class of nondifferentiable mathematical programming problems we consider a converse duality result with respect to a higher order Mond-Weir dual. AMS Mathematics Subject Classification: 90C29, 90C30, 90C32.

A 41-year-old woman presented with burning and erythema in her extremities triggered by warmth and activity, which was relieved by applying ice. Extensive workup was consistent with adult-onset primary erythromelalgia (EM). Several pharmacological treatments were tried including local anesthetics, capsaicin, ziconotide, and dantrolene, all providing 24-48 hours of relief followed by symptom fla...

Nav1.3 TTX-sensitive, voltagegated sodium channel Embryonic DRG and TG neurons, spinal cord, and thalamus; upregulated in DRG and dorsal horn neurons following nerve injury Loss of function attenuates pain-related behavior Na+ channel blockers including local anesthetics, anticonvulsants, antiarrhythmic, and TCAs relieve pain associated with neuropathy, diabetes, osteoarthritis, and surgery. Mu...

Adult-onset erythromelalgia (EM) is a rare disease characterized by episodic bouts of burning pain and erythema for which the optimal therapy is unclear. In this report, we describe a 68-year-old Japanese woman with adult-onset EM. Intravenous administration of methylprednisolone sodium succinate 1,000 mg/day dramatically improved her pain as evaluated by the visual analog scale. Although the p...

The skin may exhibit the first clinical evidence of a systemic disease and may provide the first clues to a diagnosis in malignancies. Erythroderma is defined as generalized redness and scaling and it is a clinical manifestation of a variety of underlying diseases including, rarely, solid tumors. Breast cancer is associated with a variety of skin paraneoplastic manifestations like acanthosis ni...

A 40-year-old woman had had, for 5 years, episodes of pallor and blue discoloration of the fingers and toes after cooling and emotional exertion. During these 5 years she also had intolerance to warming of the feet, which manifested attacks of pulsating pain and burning sensations. She had about ten cold and five to seven hot induced paroxysms daily. There were no trophic changes or edema of th...

A 25-YEAR-OLDwhitemanpresentedwithalifelong history of severe, sometimes excruciatingpain inhis legs,whichwereconstantly red and hot. He insisted on having his legs and feet constantly in ice water to relieve his severe discomfort. He required treatment with oxycodone and acetaminophen (Percocet) every 4 hours for pain. His mother recalled that from the age of 2 years his feet and legs intermit...