A fixed drug eruption (FDE) is characterized by the presence of a solitary or multiple, pruritic, well-circumscribed, erythematous plaques. These lesions have tendency to recur at same sites and heal with residual hyperpigmenation. With repeated attacks, the size and/or number of the lesions may increase. So far, more than 100 drugs have been implicated in causing FDEs, including ibuprofen, sul...

abstract fixed drug eruption (fde) is a unique type of cutaneous drug reaction that typically recurs in the identical locations on re-exposure to the attributed drug. fde is characterized by the appearance of a single or multiple sharply demarcated violaceous erythematous plaques which heal with residual hyperpigmentation. a 27-year-old woman presented with multiple dark patches over her eyelid...

Background: Netherton syndrome is a rare autosomal recessive disorder consisting of ichthyosiform dermatosis, hair shaft abnormalities and an atopic diathesis that presents as widespread erythematous skin. The aim of these reports is emphasis on the importance of the examination of hair as a diagnose route. Case presentation: Case 1: A 6 months old boy with respiratory distress and severe eryth...

A 52-year-old woman sought medical attention because of several annular erythematous lesions with central clearing on her body since seven months ago. No pruritus or burning sensations were noted. Her medical and family history was unremarkable. Her Fitzpatrick skin photo-type was II. On dermatological physical examination, there were several annular erythematous plaques with raised borders and...

It is now recognized that there is a two-way interaction between Helicobacter pylori gastritis and gastric physiology. H. pylori gastritis can alter gastric physiology, leading to increased or decreased acid secretion depending on the pattern of gastritis present. These changes in physiology are related to the disease outcome, with increased acid secretion leading to duodenal ulcer disease and ...

R ETICULAR ERYTHEMATOUS MUCINOSIS (REM) is a rare chronic dermatosis that is typically characterized by reticular macular erythema or erythematous papules and plaques on the central area of the chest and back of middle-aged women. The pathogenesis and etiology of REM remain undefined at present. Several factors have been associated with the induction of the syndrome, including viral processes, ...

A 57-year-old man presented with a one-month history of photosensitivity (Figures 1, 2). On physical examination erythematous patches affected all parts of his face and dorsum of both hands. Interestingly the erythematous rash affected the dorsum of hands between the joints but the joints were spared. All laboratory tests were within normal range. A skin biopsy was performed, and histopathologi...