OBJECTIVE Reduced levels and impaired function of endothelial progenitor cells (EPCs) foster development and progression of atherosclerotic lesions. Endothelial nitric oxide synthase (eNOS)-derived NO regulates EPC mobilization and function. Organic nitrates release NO, and therefore may favorably affect EPC biology. METHODS AND RESULTS We compared the effects of 2 different nitrates on circu...

BACKGROUND Stromal cell-derived factor-1 (SDF1) and its receptor CXC chemokine receptor 4 (CXCR4) play a critical role in progenitor cell homing, mobilization and differentiation. It would be interesting to assess the predictive value of SDF-1alpha level for EPC number, and to ascertain whether there is a relationship between SDF1 gene variation, plasma SDF-1alpha level, and the number and func...

Presentation of music as vibration to the skin has the potential to facilitate interaction between musicians with hearing impairments and other musicians during group performance. Vibrotactile thresholds have been determined to assess the potential for vibrotactile presentation of music to the glabrous skin of the fingertip, forefoot and heel. No significant differences were found between the t...

(1.1) { − ·· u= nu+ g(t, u), t ∈ (0, π), u(0) = u(π) = 0, where n ∈ N and g : [0, π] × R → R is a continuously differentiable function satisfying the following assumptions: (g1) g(t, 0) ≡ 0. (g2) lim|s|→∞ g′ s(t, s) = 0 uniformly in t ∈ (0, π). (g3) There exists R0 > 0 such that g(t, s)s > 0 for any s ∈ R with |s| ≥ R0 and for a.e. t ∈ (0, π). (g4) There exist some positive numbers C1, C2, R1 a...

Resumo O estudo descreve a criação e validação da Escala de Percepção Corrupção (EPC), que se propõe avaliar como o cidadão percebe corrupção. Na construção EPC, em etapa qualitativa, instrumento foi avaliado por especialistas, seguido pré-teste. Já na quantitativa, realizou-se análise fatorial exploratória confirmatória, totalizando amostra 1075 casos. Por fim, sugere-se uma metodologia para a...

Next-generation RNA sequencing was employed to determine the acute and subchronic impact of peristaltic pulse external pneumatic compression (PEPC) of different target inflation pressures on global gene expression in human vastus lateralis skeletal muscle biopsy samples. Eighteen (N = 18) male participants were randomly assigned to one of the three groups: (1) sham (n = 6), 2) EPC at 30-40 mmHg...

Patients with end-stage renal disease (ESRD) on hemodialysis have an increased risk of cardiovascular disease (CVD). Circulating endothelial progenitor cells (EPC) contribute to vascular regeneration and repair, thereby protecting against CVD. However, circulating smooth muscle progenitor cells (SPC) may contribute to adverse vascular remodeling. We hypothesized that an imbalance occurs between...

Abstract Bead foams made from standard polymers such as expanded polystyrene (EPS) or polypropylene (EPP) are widely used in everyday products. In order to expand the application window of bead foams, industry, automotive industry among others, is striving for higher‐performance materials create a lightweight material high‐temperature applications. New polycarbonate (EPC) emerging offer wider r...

OBJECTIVE Circulating endothelial progenitor cells (EPCs) correlate negatively with obesity. Previous studies have shown that exercise significantly restores circulating EPC levels in obese people; however, the underlying mechanisms have not been elucidated. Recently, irisin has been reported to have a critical role in the regulation of EPCs. This exercise-induced myokine has been demonstrated ...

angioedema is characterized by recurrent, circumscribed, solitary or multiple subcutaneous and mucosal swelling, involving the extremities, face, larynx, bowel wall. angioedema is due to hereditary or acquired varieties of c1 esterase inhibitor (c1inh) deficiency. a case of atypical acquired angioedema in a 49-year old man, responding favourably to cinnarizine and alcohol abstinence, is present...