condition of unknown etiology that is characterized by eosinophilic infiltration in the layers of the gastrointestinal tract [1]. It can affect any part of the gastrointestinal tract but most commonly affects the stomach [1,2]. This report describes a rare case of EGE presenting as a perforated duodenal ulcer with subsequent duodenal stenosis. A 26-year-old manwas referred to us with duodenal o...

Introduction Eosinophilic gastroenteritis is an uncommon disease characterized by peripheral eosinophilia and eosinophilic infiltration of the gastrointestinal tract. The bone marrow shows a reactive eosinophilia and the symptoms and signs usually reflect the layer of bowel which is most severely affected. Predominant mucosal disease may be associated with malabsorption, muscle disease with obs...

Eosinophilic oesophagitis is an inflammatory condition associated with marked eosinophil accumulation in the mucosal tissues of the oesophagus. Eosinophils are major pro-inflammatory cells thought to make a significant contribution to allergic diseases that affect the upper and lower airways, skin, and gastrointestinal tract. Type 2 cytokines such as interleukin (IL)-5 and IL-13 are central to ...

Clonal eosinophilic disorders are rare among hematological malignancies. Most eosinophilia tends to be due to secondary causes such as infections, hypersensitivity conditions, drug reactions, and connective tissue disorders. The presence of a primary clonal eosinophilic disorder such as chronic eosinophilic leukemia-not otherwise specified (NOS) in the presence of a synchronous large cell lymph...