Carmen Garnacho, Vladimir Shuvaev, Anu Thomas, Lindsey McKenna, Jing Sun, Michael Koval, Steven Albelda, *Vladimir Muzykantov, and *Silvia Muro Dept. of Pharmacology, Targeted Therapeutics Program of the Institute for Translational Medicine and Therapeutics, Institute for Environmental Medicine, Pulmonary Critical Care Division of the Dept. of Medicine, School of Medicine, University of Pennsyl...

1National Center for Environmental Assessment, Office of Research and Development, US Environmental Protection Agency, Washington, DC 20460, USA 2Department of Occupational and Environmental Health, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada H3T 1A8 3National Health and Environmental Effects Research Laboratory, Office of Research and Development, US Environmental Protect...

BACKGROUND During the last 5 years a fundamental curriculum reform was realized at the medical school of the Ludwig-Maximilians-University. In contrast to those efforts, the learning objectives were not defined consistently for the curriculum and important questions concerning the curriculum could not be answered. This also applied to Occupational and Environmental Medicine where teachers of bo...

Personalised health surveillance is infrequent or absent in occupational and environmental medicine. The shortage of functional tests in relevant cells and tissues greatly limits our understanding of environmental exposures and associated disease risk. We evaluated single cell signalling in peripheral blood mononuclear cells from 301 individuals in a cross sectional health survey 18 months afte...

Recent developments in biomedical sciences and environmental medicine have significantly improved our understanding of risk factors associated with human diseases and health disparities. Although poor access to health care, genetic, cultural, behavioral, and socio-economic factors have been linked to disease status, environmental determinants including physical, chemical, and biological factors...

The prevention of cancer by the elimination of, or decreased contact with, chemical carcinogens is dealt with under three headings. (a) Exposure of special groups: occupational cancer, iatronic cancer; (b) exposure of whole populations; (c) discovery of chemical carcinogens in the course of toxicity studies. It is most important that a major effort be made to interrelate findings in man with th...

Asthma is a global public health problem and the most common chronic disease among children. The factors associated with the condition are diverse, and environmental factors appear to be the leading cause of asthma exacerbation and its worsening disease burden. However, it remains unknown how changes in the environment affect asthma over time, and how temporal or environmental factors predict a...