BACKGROUND Apolipoprotein A-IV (apoA-IV) is an anti-atherogenic and anti-oxidative plasma glycoprotein involved in reverse cholesterol transport. The aim of this study was to examine the association between apoA-IV and all-cause mortality, cardiovascular endpoints and parameters of protein-energy wasting and nutrition in haemodialysis patients. METHODS This post hoc analysis was performed in ...

BACKGROUND The optimal nutrition approach for the promotion of weight gain in HIV-infected adults with wasting remains unclear. Previous dietary interventions report minimal success and provide inadequate information regarding the counseling approach, contact time, session format, and issues addressed with the subject. The methods we report were incorporated in a 12-week intervention trial for ...

Among the many risk-factors that affect the outcomes of Chronic Kidney Disease (CKD), especially End-Stage-Renal-Disease, and on Maintenance Hemodialysis (MHD), Protein-Energy-Wasting (PEW) of CKD plays a major role [1-5]. Evaluating nutritional status is a critical component of physiologic health and fundamental to identifying PEW. Multiple studies indicate that PEW is closely associated with ...

OBJECTIVES To determine wasting prevalence among infants aged under 6 months and describe the effects of new case definitions based on WHO growth standards. DESIGN Secondary data analysis of demographic and health survey datasets. SETTING 21 developing countries. POPULATION 15 534 infants under 6 months and 147 694 children aged 6 to under 60 months (median 5072 individuals/country, range...

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Growing evidence suggests acute skeletal muscle wasting is a key factor affecting nutritional support and prognosis in critical patients. Previously, plenty of studies of muscle wasting focused on the peripheral pathway, little was known about the central role. We tested the hypothesis whether central inflammatory pathway and neuropeptides were involved in the process. In lipopolysaccharide (LP...

Dear Editor, We read with great interest the recent article comparing the mechanisms under muscle wasting in quadriceps and diaphragm using an animal model by Mangner et al. While muscle wasting in heart failure (HF) patients is associated with poor exercise capacity and prognosis, current clinical evidences in therapeutic approach have been limited to ones by exercise training. As the author r...

BACKGROUND Progressive loss of skeletal muscle, termed muscle wasting, is a hallmark of cancer cachexia and contributes to weakness, reduced quality of life, as well as poor response to therapy. Previous studies have indicated that systemic host inflammatory response regarding tumor development results in muscle wasting. However, how tumor directly regulates muscle wasting via tumor-derived sec...

Huntington's disease (HD), a neurodegenerative disorder caused by mutant huntingtin, is characterized by a catabolic phenotype. To determine the mechanisms underlying muscle wasting, we examined key signal transduction pathways governing muscle protein metabolism, apoptosis, and autophagy in R6/2 mice, a well-characterized transgenic model of HD. R6/2 mice exhibited increased adiposity, elevate...