Background Transsphenoidal secondary operations are a minority but not rare occurrence. How to viably prevent cerebral fluid (CSF)-related complications and confine surgery-caused injury in surgery as minimally possible is huge challenge. This article shares our solution of recycling prior Hadad-Bassagasteguy flap (HBF) along with using small piece free autologous mucosa reconstruct the skull b...

Spontaneous reossification of the sellar floor after transsphenoidal surgery has been rarely reported. Strontium ranelate, a divalent strontium salt, has been shown to increase bone formation, increasing osteoblast activity. We describe an unusual case of a young patient with Cushing's disease who was treated with strontium ranelate for low bone mass who experienced spontaneous sellar reossific...

BACKGROUND Direct comparisons of microscopic and endoscopic resection of sellar lesions are scarce, with conflicting reports of cost and clinical outcome advantages. OBJECTIVE To determine if the proposed benefits of endoscopic resection are realized on a population level. METHODS We performed a matched cohort study of 9,670 adult patients in the MarketScan database who underwent either end...

UNLABELLED To describe a series of 129 consecutive patients submitted to the resection of pituitary tumors using the endoscopic transsphenoidal approach in a public medical center. METHOD Retrospective analysis based on the records of patients submitted to the resection of a pituitary tumor through the endoscopic transsphenoidal approach between 2004 and 2009. RESULTS One hundred and twenty...

OBJECTIVE Endoscopic endonasal (transnasal) transsphenoidal approach (EETA) for management of sellar lesions has gained popularity as a reliable and atraumatic method. Most reported studies of EETA have focused on surgical outcome in adult patients; and there are few reports to describe outcome in pediatric patients. The authors report our early experience of 11 patients aged 14 to 18 years man...

Olfactory outcomes as well as oronasal postoperative complications of transsphenoidal pituitary surgery have not been well studied. The objective of this study was to investigate nasal symptoms including olfactory function as well as quality of life following transsphenoidal pituitary surgery. The study is designed as a prospective cohort study set in a single tertiary hospital. A total of 53 p...