Endometriosis is a benign, estrogen-dependent disease with symptoms such as pelvic pain and infertility, and it is characterized by the ectopic distribution of endometrial tissue. The expression of the ID2, PRELP and SMOC2 genes was compared between the endometrium of women without endometriosis in the proliferative phase of their menstrual cycle and the eutopic and ectopic endometrium of women...

OBJECTIVE This study aimed to evaluate the levels of two oxidative stress (OS) markers including lipid peroxide (LPO) and total antioxidant capacity (TAC) in both serum and follicular fluid (FF) of women with endometriosis after puncture. MATERIALS AND METHODS In this cross-sectional study, a total number of sixty-three women younger than 40 years old with laparoscopy (gold standard for endom...

OBJECTIVES The study included patients suffering from stage III-IV endometriosis complicated by an endometrioma (OMA). We investigated the association between age, presence of dysmenorrhea/dyspareunia, preoperative CA 125 level, size of OMA on ultrasonographic exam and infertility as well as the risk of intraoperative detection of hydrosalpinx that was not suspected on pre-operative assessment....

BACKGROUND Many epidemiological studies have suggested an association between estrogen receptor-beta (ER-β) polymorphisms with endometriosis risk. However, the results of these studies have been inconsistent. In the present study, we performed a meta-analysis to clarify the associations between the ER-β rs4986938 and rs1256049 polymorphisms and endometriosis risk. METHODS Eligible publication...

background: endometriosis is defined as the existence of endometrial-like tissue outside the uterus. diagnosis of endometriosis is a challenging theme. despite the broad search for innovative laboratory tests and advances in imaging technologies, there are still no easy, non-invasive diagnostic tests available. due to inflammatory process of endometriosis, still c-reactive protein (crp) level m...

Endometriosis is one of the most common gynecological diseases affecting up to 10% of the female population of childbearing age and a major cause of pain and infertility. It is influenced by multiple genetic, epigenetic and environmental factors. Interleukin‑16 (IL‑16) is a proinflammatory cytokine playing a pivotal role in many inflammatory and autoimmune diseases as well as in the pathogenesi...

BACKGROUND Endometriosis is a chronic gynecological benign disease that shares several features similar to malignancy. Mitochondrial DNA (mtDNA) mutations have been reported in all most all types of tumors. However, it is not known as to whether mtDNA mutations are associated with endometriosis. METHODOLOGY We sequenced the entire mitochondrial genome of analogous ectopic and eutopic endometr...

Endometriosis is a disease associated with the presence of tissue morphologically similar to endometrium outside uterine cavity and it an important medical social problem. Statistical analysis endometriosis prevalence complicated by polymorphism manifestations gradual increase symptoms long period time from first diagnosis. Manifestations are chronic pain, algodismenorea, dyspareunia, decreased...

it seems that endometriosis plays an important role in female factor infertility but a clear causal relationship has yet to be established. this case-control study was conducted to determine and compare the frequency and severity of endometriosis in 100 infertile women and 120 fertile multi-para women as control group. descriptive statistics, student t test and chi square test were used in anal...

BACKGROUND Endometriosis is a heritable common gynaecological condition influenced by multiple genetic and environmental factors. Genome-wide association studies (GWASs) have proved successful in identifying common genetic variants of moderate effects for various complex diseases. To date, eight GWAS and replication studies from multiple populations have been published on endometriosis. In this...