Hypothalamic nesfatin-1, derived from the nucleobindin2 (NUCB2) precursor, inhibits nocturnal food intake and body weight gain in rats. Nesfatin-1 is able to cross the blood-brain barrier, suggesting a peripheral source of nesfatin-1. Many centrally acting food intake regulatory neuropeptides are also produced in the periphery, especially in the gastrointestinal tract. Therefore, we investigate...

Now in its sixth year, Endocrine Connections was the first Open Access journal devoted to hormones. The journal is owned by two well-established endocrine learned societies, the European Society of Endocrinology (ESE) and the Society for Endocrinology (SfE). In 2016, Endocrine Connections was included in the Science Citation Index Expanded (SCIE) and expects its first impact factor in Thomson R...

aims of the study: endometriosis is a prevalent gynecologic disorder in young women at reproductiveage but the underlying risk factors have not identified yet in iran and other neighboringcountries. persistent exposure to environmental endocrine disrupting chemicals (edcs) in particulardioxins, pahs and polychlorinated biphenyls (pcbs) with xenoestrogenic potentials have beenhypothesized in the...

Endoscopic ultrasound (EUS) enables detection and localization of pancreatic neuroendocrine tumours. Even small tumours down to a diameter of 1-2 mm can be visualized. Since such small tumours usually cannot be detected by computed tomography (ct), magnetic resonance imaging (mri) and somatostatin receptor scintigraphy (srs), and experience with EUS imaging is limited, there is no clear evidenc...

INTRODUCTION AND OBJECTIVE pancreatic endocrine tumors (PET) are difficult to diagnose. Their accurate localization using imaging techniques is intended to provide a definite cure. The goal of this retrospective study was to review a PET series from a private institution. PATIENTS AND METHODS the medical records of 19 patients with PETs were reviewed, including 4 cases of MEN-1, for a period ...

OBJECTIVE The surgical management of primary hyperparathyroidism (PHPT) has undergone considerable advances over the past two decades. The purpose of this report is to review these advances. PARTICIPANTS This subgroup was constituted by the Steering Committee of the Fourth International Workshop on the Management of Asymptomatic Primary Hyperparathyroidism to address key questions related to ...

Thyroid cancer, which represents the most common tumors among endocrine malignancies, comprises a wide range of neoplasms with different clinical aggressiveness. One of the most important challenges in research is to identify mouse models that most closely resemble human pathology; other goals include finding a way to detect markers of disease that common to humans and mice and to identify the ...

Endocrine-disrupting chemicals have the ability to interfere with and alter functions of hormone system, leading adverse effects on reproduction, growth development. Despite growing concerns over their now ubiquitous presence in environment, endocrine-related human health remain largely outside comparative toxicity characterization frameworks as applied for example life cycle impact assessments...

conclusions our case is the first report of ivus imaging of subclavian stenosis resulting from takayasu’s arteritis and provides insight into the pathology behind such lesions. introduction takayasu’s arteritis (ta) is a chronic, idiopathic, inflammatory disease that affects large elastic arteries, including the aorta and its main branches. no consensus exists currently on the superiority of su...