endocrine function

There is concern that the addition of ovarian function suppression to endocrine treatment premenopausal patients with breast cancer will increase nonadherence in this population. Although oral therapy was fairly high first year study, it not worse when combined therapy.

متن کامل

Lapatinib restores hormone sensitivity with differential effects on estrogen receptor signaling in cell models of human epidermal growth factor receptor 2-negative breast cancer with acquired endocrine resistance.

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2010

Alexandra F Leary Suzanne Drury Simone Detre Sunil Pancholi Anne E Lykkesfeldt Lesley-Ann Martin Mitch Dowsett Stephen R D Johnston

PURPOSE Acquired endocrine resistance in estrogen receptor (ER)alpha+/human epidermal growth factor receptor 2-negative (HER2-) breast cancer has been associated with modest adaptive increases in HER2, although exactly how aberrant HER2 signaling affects the ERalpha pathway is poorly understood. We investigated (a) whether the epidermal growth factor receptor/HER2 inhibitor lapatinib could rest...

متن کامل

Endocrine and paracrine controls of canine follicular development and function

Journal: :Reproduction in Domestic Animals 2017

متن کامل

Epigenetics in formation, function, and failure of the endocrine pancreas

Journal: :Molecular Metabolism 2017

متن کامل

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید