There have been no previous studies on dental maturation of prematurely born, very low birthweight (< 1500 g, VLBW) Caucasian children. This study investigated dental development and prevalence of enamel defects in a group of 55 VLBW children (mean age at dental examination 7.7 +/- 2.2 years, mean birthweight 1203 +/- 240 g, and mean gestational age 29.8 +/- 2.4 weeks) compared to 55 normal bir...

OBJECTIVES Cystinosis is a rare autosomal recessive lysosomal storage disorder with developmental and mineralization anomalies as part of its clinical presentation. The objective of this study was to provide the first systematic assessment of the craniofacial and dental characteristics associated with cystinosis. STUDY DESIGN Oral and radiographic evaluations were performed on 73 patients wit...

tabby and downless mutant mice have apparently identical defects in teeth, hair and sweat glands. Recently, genes responsible for these spontaneous mutations have been identified. downless (Dl) encodes Edar, a novel member of the tumour necrosis factor (TNF) receptor family, containing the characteristic extracellular cysteine rich fold, a single transmembrane region and a death homology domain...

BACKGROUND Early childhood caries (ECC) is a devastating form of dental decay affecting many Canadian children, especially those from northern First Nations communities. ECC is multifactorial in origin, and the notion that the principal etiology is inappropriate feeding modalities is no longer tenable. METHODS This study was conducted in the community of Garden Hill First Nation, Manitoba, to...

BACKGROUND AND AIM: Regarding the prevalence of molar incisor hypomineralization (MIH) among students and different populations and continuation of related problems, it seems necessary to assess the prevalence among students in Kerman, Iran. The aim of this study was to review the prevalence of MIH and its relation to the sex of 7-12-year-old students in Kerman during 2015-2016.METHODS: In this...

The oral aesthetic medicine has contributed increasingly to correct aesthetic defects in order to respond to the standards of beauty imposed by society. A smile with white teeth is included in these standards. However, due to several factors, such as diet, age and certain vices, the natural color of teeth tends to change. The bleaching of teeth pretends to restore the original color of the teet...

The continuously growing rodent incisor is an emerging model for the study of renewal of mineralized tissues by adult stem cells. Although the Bmp, Fgf, Shh, and Wnt pathways have been studied in this organ previously, relatively little is known about the role of Notch signaling during incisor renewal. Notch signaling components are expressed in enamel-forming ameloblasts and the underlying str...

Enamel matrix derivative is used to promote periodontal regeneration during the corrective phase of the treatment of periodontal defects. Our main goal was to analyze the bioactivity of different molecular weight fractions of enamel matrix derivative. Enamel matrix derivative, a complex mixture of proteins, was separated into 13 fractions using size-exclusion chromatography and characterized by...

OBJECTIVE Some anti-epileptic drugs (AED) have well-known teratogenic effects. The aim of the present study was to elucidate the effect of prenatal exposure to AED and the risk of enamel defects in the primary and permanent dentition. METHODS A total of 38 exposed and 129 non-exposed children, 6-10 years of age, were recruited from the Aarhus Birth Cohort and the Department of Neurology, Vibo...

The purpose of bone tissue engineering is to employ scaffolds, cells, and growth factors to facilitate healing of bone defects. The aim of this study was to assess the viability and osteogenic differentiation of primary human osteoblasts and adipose tissue-derived mesenchymal stem cells from various donors on titanium dioxide (TiO2) scaffolds coated with an alginate hydrogel enriched with ename...