نتایج جستجو برای: embryonal rhabdomyosarcoma
تعداد نتایج: 24466 فیلتر نتایج به سال:
Rhabdomyosarcoma (RMS) is a malignant tumor of mesenchymal origin typically affects children and adolescents, with an annual incidence of 4.3 cases per 1 million population aged <20 years. Para testicular RMS is rare, constituting 4-7% of all RMS in children and young adults. Here we report a case of 16-year old boy with right paratesticular solid mass. Ultrasound revealed vascular paratesticul...
In order to explore the potential of immune checkpoint blockade in sarcoma, we investigated expression and clinical relevance of programmed cell death-1 (PD-1), programmed death ligand-1 (PD-L1) and CD8 in tumors of 208 sarcoma patients. Primary untreated osteosarcoma (n = 46), Ewing sarcoma (n = 32), alveolar rhabdomyosarcoma (n = 20), embryonal rhabdomyosarcoma (n = 77), synovial sarcoma (n =...
BACKGROUND We report the case of an adult patient with embryonal rhabdomyosarcoma of the perineum admitted to our practice at Joliot Curie Institute in Dakar. It is a rare tumor at this age and has a bad prognosis at this localization. CASE PRESENTATION We describe the case of a 22-year-old African man admitted for a perineal mass that had evolved over 6 months. He complained of tenesmus, obs...
A 54-year-old woman presented with intractable perianal, bilateral buttock, and radiating thigh/calf pain. An MRI scan showed an intradural, contrast-enhancing, ovoid mass in the cauda equina region at L1-L2. At laminectomy, the ovoid mass arose from a nerve root and, intact, was gross totally resected. Histologically, the dominant pattern was that of schwannoma. One year thereafter, the sympto...
Alveolar and embryonal rhabdomyosarcomas are childhood tumors that do not respond well to current chemotherapies. Here, we report that the glycolytic inhibitor 2-deoxyglucose (2-DG) can efficiently promote cell death in alveolar, but not embryonal, rhabdomyosarcoma cell lines. Notably, 2-DG also induced cell differentiation accompanied by downregulation of PAX3/FOXO1a, the chromosome translocat...
Perivascular epithelioid cell tumours (pecomas) are rare mesenchymal tumours that are characterized by perivascular epithelioid cell differentiation and immunoreactivity to myogenic and melanocytic markers. These tumours can be classified as benign, uncertain malignant potential, or malignant. Because of the rarity of pecomas, their cause and clinical prognosis remain unclear. To the best of ou...
Background & Aim: Rhabdomyosarcoma is the most frequent soft tissue tumor in children with prevalence of 5-8% among childhood cancers. The survival of patients are related to some factors such as primary site of tumor, histology, stage of disease, early diagnosis and treatment. The survival rate of these patients has significantly increased since the 1970s. Considering the variety of report...
Primary rhabdomyosarcoma of the central nervous system (CNS) is rare in both adults and children (Taratuto et al. (1985) Acta Neuropathol (Berl) 66(2): 98–104). The outcome in the majority of cases is poor, and many cases are associated with early mortality (Celli et al. (1998) J Neurooncol 36(3):259–267). There are very few cases reported in the literature of survival beyond 2 years after diag...
BACKGROUND Embryonal rhabdomyosarcoma in a form of a polyp of the uterine cervix occurs mainly in young women in their second decade of life. The characteristic microscopic features are: the submucosal cambium layer and the presence of rhabdomyoblasts in the stroma. So far the treatment has not been well defined and ranges from conservative to radical surgery CASE The presented case is a 22-y...
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