Five antibiotics-penicillin, streptomycin, aureomycin, chloromycetin, and terramycin-are now readily available for the treatment of diseases due to bacterial infection, and for the treatment of wounds infected either primarily or by hospital cross-infection. There is considerable overlapping in the selective activity of these antibiotics in that they are effective against Gram-positive bacteria...

In recent months a series of papers have appeared, namely by Price and Rittenberg (1950), Plaut and Lardy (1950), and Sakami (1950), which indicate that acetone is utilized by mammalian tissue. Several metabolic pathways have been proposed for this oxidation. Plaut and Lardy (1950) concluded that acetone was directly incorporated into acetoacetate by a mechanism involving C02 fixation. Price an...