Abstract Objective Myeloid neoplasms (MNs) harboring inv(3)(q21q26)/t(3;3)(q21;q26) or MECOM gene rearrangements as identified by fluorescence in situ hybridization (FISH) are known to carry a poor prognosis. The objective of this study is assess prognostic impact MNs with copy number alterations (CNA) compared inv(3)/t(3;3) rearrangements. We present those initial comparative results and secon...

Iron-based amorphous metallic alloys (AMAs) of several compositions were exposed to neutron irradiation with fluences up 1019 n/cm2. These materials exhibit excellent magnetic properties which predetermine them for use in electronic devices operated also radiation-exposed environments. Response the studied AMAs is followed by Mössbauer spectrometry probes local microstructure. Neutron leads rea...

Pnp-switchable semiconductor materials are capable of switching their electronic properties from p- to n-type conduction. Observed in the handful discovered compounds, this behavior is usually accompanied by a temperature-dependent phase transition. During transition, dynamical rearrangement certain substructure enables change predominant charge carrier type. Considering immense demand for comp...

The hydrogen storage capacity of Pd nanoparticles (NPs) decreases as the particles become smaller; however, this reduced is ameliorated by addition Pt. In present work, mechanism and structural transformations core (Pd)–shell (Pt) (CS) solid-solution (SS) NPs during absorption desorption (PHAD) processes are investigated. situ X-ray spectroscopy measurements were performed to study evolution el...

Thermal rearrangement of spirans (14) and (31) yields the xanthones (16,34) and diphenylrnethane (15, 32), respectively. The structure for xanthone (16), isolated from thermolysis, has been established by reduction to xanthene (20) followed by reoxidation to give xanthone (16). Alternatively, methylation of the diphenylmethane (15) followed by heating with selenium dioxide also yields xant...

It has been of interest whether and when the rearrangement of neuronal circuits can be induced after projection patterns are formed during development. Earlier studies using cats reported that the rearrangement of retinogeniculate projections could be induced even after eye-specific segregation has occurred, but detailed and quantitative characterization of this rearrangement has been lacking. ...

INTRODUCTION The rearrangement of the anaplastic lymphoma kinase (ALK) gene accounts for approximately 1%-6% of lung adenocarcinoma cases and defines a molecular subgroup of tumors characterized by clinical sensitivity to ALK inhibitors such as crizotinib. This study aimed to identify the relationship between ALK rearrangement and the clinicopathologic characteristics of non-small cell lung can...

Recently, ETS-related gene (ERG) gene rearrangements, phosphatase tensin homologue (PTEN) deletions and EGFR family aberrations were characterized as potential biomarkers for prostate cancer (PCa) patient management. Although ERG gene rearrangement has been identified in approximately 50% of localized prostate cancers in western countries, the prognostic significance of this critical molecular ...

Immunoglobulin genes are generated during differentiation of B lymphocytes by joining gene segments. A mouse pre-B cell contains a functional immunoglobulin heavy-chain gene, but no light-chain gene. Although there is only one heavy-chain locus, there are two light-chain loci: kappa and lambda. It has been reported that kappa loci in the germ-line configuration are never (in man) or very rarely...

OBJECTIVE To explore the relationship between IgH gene rearrangement and orbital MALT (mucose-associated lymphoid tissue) lymphoma removal operation prognosis, and to quantify the effect of IgH gene rearrangement on primary orbital MALT lymphoma prognosis. PATIENTS AND METHODS Fifty-eight patient cases with primary orbital MALT lymphoma were included in this study. Orbital lymphoma specimens ...