Systolic time intervals (STI) are sensitive indices of myocardial function. The present study was conducted to evaluate the effect of orthostatic stress on STI before and after 70 degrees head up tilt (HUT) in rabbits. Electrocardiogram (ECG), phonocardiogram and carotid arterial pulse were recorded simultaneously on four channel polyrite (INCO). Within 1 second of tilt there was a significant ...

PURPOSE To evaluate myocardial contractility during ST segment depression in healthy parturients during Cesarean section (CS). METHODS Forty-seven consecutive term parturients undergoing elective CS under spinal anesthesia were studied. The ST segment was recorded continuously on leads II and V5 using a Holter monitor. Myocardial performance was evaluated by measuring cardiac index (CI), hear...

AIMS To study global and regional left atrial (LA) mechanics in chronic primary mitral regurgitation (MR) with echocardiography. METHODS AND RESULTS LA volumes during reservoir, conduit, and contractile phases were measured in 27 MR patients and 25 controls. LA ejection fraction (EF) and ejection force were calculated. Reservoir (SR-R), conduit (SR-C), and contractile phase (SR-A) strain rate...

AIMS Left ventricular ejection fraction (EF) is a suboptimal measure of ventricular function. Recent mathematical modelling of left ventricular contraction has shown that the EF is determined by both myocardial shortening (strain) and by end-diastolic wall thickness. Increasing end-diastolic wall thickness resulted in augmented radial wall thickening. This may result in a significant 'overestim...

Abstract: Coronary artery disease (CAD) is a multifactorial problem. Although hyperlipidemia (HLP), diabetes (DM), and hypertension (HTN) are known as the familial and cardiac risk factors, CABG is rare in the several members of a family. We reported the six members of a family who presented with MI and/or advanced angina pectoris during the 6 years. CABG(Coronary artery bypass graft) considere...

Heart failure with preserved ejection fraction(HFpEF) is an entity showing upward trend. The affected populationis rising on account of rise in the geriatric population as well expanding incidence comorbidities,thusunderlining necessity greater therapeutic avenues. underlying disease mechanisms are complicated.Irrespective EF, HFpEF negatively influences quality life and hard clinical endpoints...

BACKGROUND In clinical heart failure (HF), inefficient propagation of blood through the left ventricle (LV) may result from suboptimal vortex formation (VF) ability of the LV during early diastole. We aim to (i) validate echocardiographic-derived vortex formation time (adapted) (VFTa) in control subjects and (ii) examine its utility in both systolic and diastolic HF. METHODS Transthoracic ech...

Sudden cardiac death (SCD) in patients with ischemic heart disease remains a leading cause of death. Prediction who is at risk based on the left ventricular ejection fraction (EF). However, majority victims SCD have normal EF, and implanted an implantable cardioverter- defibrillator their EF are never treated by device. Several parameters could allow better prediction SCD. signs ECG Periodic Re...

Abstract Introduction The gold standard for the evaluation of ventricular function is currently echocardiographic measured ejection fraction (EF). However, use this parameter has limitations, which are more important in populations with afterload mismatch and especially when severe. On other hand, assessment a pump fluid dynamics done using head pressure, product pressure flow zero. During card...

BACKGROUND The aim of this study was to prospectively examine echocardiographic parameters that correlate and predict functional capacity assessed by 6 min walk test (6-MWT) in patients with heart failure (HF), irrespective of ejection fraction (EF). METHODS In 147 HF patients (mean age 61 ± 11 years, 50.3% male), a 6-MWT and an echo-Doppler study were performed in the same day. Global LV dys...