نتایج جستجو برای: edaravone

تعداد نتایج: 529  

2017
Jun Sun

Amyotrophic lateral sclerosis (ALS), also called Lou Gehrig’s disease, is a neuromuscular disease characterized by a progressive death of motor neurons and muscle atrophy. Most ALS patients die within 5 years of disease onset. Currently, treatment with the US Food and Drug Administration (FDA) approved drug, Riluzole, merely extends the patient’s life span for a few months. For the second time ...

Journal: :Molecules 2012
Chengyuan Liang Hailong Jiang Zhiguang Zhou Dong Lei Yu Xue Qizheng Yao

An efficient and convenient approach for one-pot synthesis of 3-substituted chroman-2,4-diones via a three-component reaction of aromatic aldehydes, 4-hydroxy-coumarins and diverse pyrazolone derivatives was described. The combinatorial synthesis for this methodology was achieved by applying ultrasound irradiation in the absence of activator while making use of water as green solvent. Additiona...

2013
Kimihiro Nagatani Hiroshi Nawashiro Satoru Takeuchi Satoshi Tomura Naoki Otani Hideo Osada Kojiro Wada Hiroshi Katoh Nobusuke Tsuzuki Kentaro Mori

BACKGROUND Most of the results regarding hydrogen (H2) therapy for acute cerebral ischemia are derived from in vitro studies and animal experiments, with only a few obtained from human trials with a limited number of subjects. Thus, there is a paucity of information regarding both the beneficial therapeutic effects as well as the side effects of H2 on acute cerebral ischemia in humans. We desig...

Journal: :Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 2017

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