BACKGROUND Hand eczema risk factors are potentially associated with lifestyle, and changes in lifestyle may influence the prevalence of this condition. OBJECTIVES To report potential lifestyle risk factors and their association with hand eczema. PATIENTS/MATERIALS/METHODS Cross-sectional questionnaire survey and standard patch test among Swedish upper secondary school children. The particip...

Research from the 1930s to the 1950s established that a deficit of n-6 essential fatty acids (EFAs) leads to an inflammatory skin condition in both animals and humans. In a common inherited skin condition, atopic dermatitis (eczema), there was evidence of low blood EFA concentrations and of a therapeutic response to exceptionally high doses of linoleic acid. More recently, it has been establish...

BACKGROUND Nummular eczema is an idiopathic inflammatory skin disease that mostly has a chronic and relapsing course. Many factors are thought to be responsible for this condition, such as atopic dermatitis, dry skin, emotional stress or seasonal variation. OBJECTIVE The purpose of the study was to assess clinical findings and aggravating factors of nummular eczema and to evaluate characteris...

BACKGROUND Long-term follow-up was completed in 84 mother-infant pairs of 118 women who completed a randomized controlled trial of prenatal supplementation with EPA- or DHA-rich fish oil or soy oil placebo. The goal of this study was to determine whether prenatal omega-3 fatty acid supplementation protects offspring against development of early childhood allergies. METHODS AND FINDINGS Assess...

BACKGROUND The recent increase in the prevalence of allergic disorders might be a consequence of increased intake of n-6 polyunsaturated fatty acids (PUFAs) and reduced intake of n-3 PUFAs. The current cross-sectional study examined the association between intake levels and the prevalence of eczema and rhinoconjunctivitis in Japanese children. METHODS Subjects were 23,388 schoolchildren aged ...

BACKGROUND The prevalence of eczema varies markedly across the globe. It is unclear whether the geographic variation is due to race and/or ethnic differences, environmental exposures, or genetic factors. OBJECTIVE We investigated the effects of ethnicity and environmental exposures on eczema in Hispanic white and non-Hispanic white children who participated in the Southern California Children...

BACKGROUND Parents and carers of children with eczema often underuse emollient therapy, essential to repairing and protecting the defective skin barrier in atopic eczema. Educational interventions delivered by specialist dermatology nurses in hospital settings have been shown to improve emollient use and reduce symptoms of atopic eczema, but benefits of community-based interventions are uncerta...

BACKGROUND The Patient-Oriented Eczema Measure (POEM) has been recommended as the core patient-reported outcome measure for trials of eczema treatments. Using data from the Choice of Moisturiser for Eczema Treatment randomized feasibility study, we assess the responsiveness to change and determine the minimal clinically important difference (MCID) of the POEM in young children with eczema. ME...

Atopic dermatitis is a chronic inflammatory skin disease that is considered familial with allergic features. It often occurs in patients with other atopic disorders such as asthma and allergic Rhinitis. The terms "dermatitis" and "eczema" are frequently used interchangeably. When the term "eczema" is used alone, it usually refers to AD (atopic eczema). "Eczematous" also connotes some scaling, c...

We investigated associations between prenatal and postnatal environmental factors onset remission of preschool childhood eczema across China. The study population was preschoolers in randomized day care centers seven cities (N = 39,782). Data on indoor outdoor environment were obtained from a cross-sectional questionnaire sent to parents or other guardians. Reports the first 2 years past year u...