A homologue of the Drosophila homothorax (hth) gene, Xenopus Meis3 (XMeis3), was cloned from Xenopus laevis. XMeis3 is expressed in a single stripe of cells in the early neural plate stage. By late neurula, the gene is expressed predominantly in rhombomeres two, three and four, and in the anterior spinal cord. Ectopic expression of RNA encoding XMeis3 protein causes anterior neural truncations ...

Transient gene expression, in plant protoplasts or specific plant tissues, is a key technique in plant molecular cell biology, aimed at exploring gene products and their modifications to examine functional subdomains, their interactions with other biomolecules, and their subcellular localization. Here, we highlight some of the major advantages and potential pitfalls of the most commonly used tr...

The purpose of this study was to identify preliminary acoustic and phonological characteristics of onomatopoetic expressions (OE) in Swedish child-directed speech. The materials on one mother interacting with her 4-year-old child were transcribed and used for pitch contour measurements on OE. Measurements were also made on some non-onomatopoetic expressions to be used as controls. The results s...

The importance of Hox genes in the specification of neuronal fates in the spinal cord has long been recognized. However, the transcriptional controls underlying their collinear expression domains remain largely unknown. Here we show in mice that the correspondence between the physical order of Hoxd genes and their rostral expression boundaries, although respecting spatial collinearity, does not...

background: the value of serial measurement of serum ß subunit of human chorionic gonadotropin (ßhcg) and ultrasonography in the early diagnosis of ectopic pregnancy has well established. objective: the objective of this study was to explore the diagnostic value of raising level of serum ßhcg, single measurement of progesterone (p) and estradiol (e2) in early diagnosis of ectopic pregnancy. mat...

Background. Tacrolimus (FK506) is effective for patients with ulcerative colitis (UC). However, there are few reports on tacrolimus therapy (TT) with respect to the relationship with endoscopic and clinicopathologic findings. Methods. Thirty patients with moderate/severe active UC refractory to or dependent on corticosteroid were treated with oral tacrolimus. The expression of ectopic MUC5AC in...

background: ovarian pregnancy is a rare form of the non-tubal ectopic pregnancy. it ends with rupture before the end of the first trimester. one of the important risk factors for ovarian pregnancy is in the use of intra uterine devices (iud). case:  we report here one such uncommon case of ovarian ectopic pregnancy. our patient is a 30 years old multiparous woman with two previous cesarean sect...

optix is a new member of the Six/so gene family from Drosophila that contains both a six domain and a homeodomain. Because of its high amino acid sequence similarity with the mouse Six3 gene, optix is considered to be the orthologous gene from Drosophila rather than sine oculis, as previously believed. optix expression was detected in the eye, wing and haltere imaginal discs. Ectopic expression...

In seed plants, the shoot apical and root apical meristems form at the apical and basal poles of the embryonic axis, and leaves form at the flanks of the shoot apical meristem. ANGUSTIFOLIA3/GRF INTERACTING FACTOR1 (AN3/GIF1) encodes a putative transcriptional co-activator involved in various aspects of shoot development, including the maintenance of shoot apical meristems, cell proliferation a...

Ectopic expression of either wild type or mutant proteins is a standard method in cell biology, and a vital part of the tool kit of molecular parasitology. During study of protein expression levels mediating intracellular trafficking, we became aware of highly variable expression between experiments. When investigated systematically it became apparent that ectopic expression of proteins from a ...