Biosynthetic and chemical datasets are the two major pillars for microbial drug discovery in omics era. Despite advancement of analysis tools platforms multi-strain metabolomics genomics, linking these information sources remains a considerable bottleneck strain prioritisation natural product discovery. In this study, molecular networking 100 metabolite extracts derived from applying OSMAC appr...

This study aimed to investigate the effects of ultra-long-term fermentation on formation non-volatile metabolites Chinese solid-fermented kohlrabies. Liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS) based non-targeted metabolomics coupled with multivariate statistical analysis were employed respectively analyze kohlrabies solid fermented for 5 years (5Y), 8 (8Y), and 11 (11Y...