Human body temperature is regulated within a very narrow range. When exposed to hyperthermic conditions, via environmental factors and/or increased metabolism, heat dissipation becomes vital for survival. In humans, the primary mechanism of heat dissipation, particularly when ambient temperature is higher than skin temperature, is evaporative heat loss secondary to sweat secretion from eccrine ...

Eccrine porocarcinoma (EPC) is a rare tumor. It develops from the intraepidermal ductal portion of the eccrine sweat gland. Metastatic disease is rare. We report a new case of metastatic eccrine porocarcinoma with a successful management and a good response to docetaxel. A 54-year-old man was admitted with a mass in the breast. Biopsy specimen found carcinomatous tumor proliferation with large ...

Giant Vascular Eccrine Spiradenoma (GVES) is a rare variant of Eccrine Spiradenoma (ES), a tumor that develops from the sweat gland. It differs from Eccrine Spiradenoma in its larger size and vascularity as well as propensity for bleeding and ulceration, which may cause a clinical misdiagnosis of vascular lesion or malignant tumor. All previously reported cases in English literature have been i...

Porocarcinoma is a very rare type of skin cancer arising from the eccrine sweat glands and poorly understood. The exact pathogenesis unknown. Clinical features are non-specific. It may present as painless, slow growing mass or nodule, ulcer, plaque, swelling, wart, papule naevus that increases in size over years to decades ulcerate bleed upon trauma. They occur equally both sexes most commonly ...

Benign and malignant neoplasm of myoepithelial cells comprise a rare but well-characterized group of tumors in the salivary glands, breasts, and soft tissues. Histopathologically, myoepitheliomas show solid, reticular, trabecular architecture and myxoid or hyaline stroma, and are composed of round/epithelioid or spindle cells. The tumor cells of myoepitheliomas possess the capacity for epitheli...

The ultrastructure of the tegument, glands and sensory organs of Pyramicocephalus phocarum (Cestoda: Diphyllobothriidea) have been studied. Three types of the microthriches are found, which have a specific distribution on the scolex and body. A welldeveloped basal lamina contained radial anchoring fibrils; they are associated with the microfibrills of the lamina reticularis and form regular cro...

A lateral dermoid cyst is a rare lesion of the floor of mouth, with only 12 cases reported in the literature. We describe the case of a 60-year-old man with a slowly enlarging mass in the submandibular region. Magnetic resonance imaging demonstrated a lesion containing multiple uniformly rounded foci, creating a "sack-of-marbles" appearance. Needle aspirations showed atypical findings, and the ...

1. Intra-arterially as well as intradermally administered adrenaline or noradrenaline produces a sweat response. 2. The intensity of the intradermal response is always considerably less than that due to acetylcholine and the threshold of effective concentration is considerably greater than for acetylcholine. The glands also fail to respond to repeated small doses of intradermal catecholamine an...