OBJECTIVE To determine the frequency of various types of cutaneous appendage tumors in our practice. METHOD This is a partly retrospective and partly prospective study conducted at the Department of Pathology, Histopathology Section, The Aga Khan University Hospital, Karachi between 1st January 1997 and 31st December 2001. RESULTS One hundred sixty six skin appendage tumors were diagnosed d...

Eccrine angiomatous hamartoma is a rare, benign tumor characterized by a proliferation of eccrine and vascular structures. We present 2 cases and review the characteristics of this disorder. The first patient was a 33-year-old woman who consulted for a brownish lesion on her back associated with local hyperhidrosis. The second patient was a 25-year-old man with an asymptomatic erythematous lesi...

Neurofibromatosis is a systemic hereditary disorder with varied manifestations in bone, soft tissue, the nervous system and skin. Cutaneous manifestations of neurofibromatosis are characterized by café-au-lait macules, multiple neurofibromas, Lisch nodules and intertriginous freckling. Some benign or malignant tumors such as juvenile xanthogranuloma, pheochromocytoma, and malignant melanoma can...

Eccrine carcinoma is an extremely rare malignant skin cancer arising from eccrine sweat glands with a high metastatic potential. It mainly occurs in the elderly, with equal incidence in both sexes. It usually spreads to regional lymph nodes, with liver, lungs, and bones being the most common sites of distant metastasis. Because of tumor rarity, little is known about the value of F18- FDG PET/CT...

MANGOS, JOHN. Transductal fluxes of Na, K, and water in the human eccrine sweat gland. Am. J. Physiol. 224(5): 1235-1240. 1973.--The bidirectional fluxes of Na, the net influx of K, and the net fluxes of water were studied in the human sweat duct in vitro by free-flow microperfusion with sweat resembling the primary secretory fluid and by microanalysis of the fluid samples obtained. Full-thickn...

Sir, Hydrocystomas are rare, benign, cystic skin tumors arising from mature, deformed sweat units which are dilated by their own secretions.[1] Depending on the gland of origin, they can either be apocrine or eccrine hydrocystomas. Eccrine hydrocystoma can either be solitary or multiple. Most commonly they affect the face and neck regions of middle-aged female patients and are often multiple.[1...

We report a rare case of giant vascular eccrine spiradenoma (GVES) which developed in 56-yr-old Korean woman. It is a rare variant of eccrine spiradenoma (ES), which might be mistaken for angiomatous lesions in view of its florid vascularity and hemorrhagic features. Histogenesis of GVES is not clearly elucidated although it is known that ES presumably originates in the eccrine glands. To clari...

INTRODUCTION Green pigmentation on the palms and soles in patients with hyperbilirubinemia is a rare entity. Eccrine chromhidrosis is an unusual form of green acral pigmentation characterized by the secretion of colored sweat from the eccrine glands. Rarely, eccrine chromhidrosis can mimic an eczematous process leading to misdiagnosis. We report a case of a patient with hyperbilirubinemia who p...

Eccrine Porocarcinoma (ECP) is a malignant tumour arising from the intraepithelial ductal parts of the sweat gland. It has also been described as malignant hidroacanthoma simplex, sweat gland carcinoma, malignant intra-epidermal eccrine poroma, eccrine poroepithelioma, dysplastic poroma, malignant syringo acanthoma and porocarcinoma. Treatment with wide local excision but metastatic lesions can...

Sir, Eccrine angiomatous hamartoma (EAH) is a rare benign hamartoma of eccrine glands and blood vessels. It most commonly develops before adulthood as a single, slowgrowing lesion on the extremities. We describe here a case of adult-onset EAH with generalized multiple hairy reddish-brown indurated plaques with a rapidly progressive course. As the lesions showed histopathological findings such a...