Recent evidence has shown that Hodgkin‘s disease (HD) is associated with Epstein-Barr virus (EBV) in a substantial number of cases and that in these cases EBV DNA is localized exclusively to Hodgkin and Reed-Sternberg (RS) cells. The virus genome is not silent in RS cells because two EBV latent gene products, latent membrane protein (LMP) and EB early region (EBER) transcripts, have recently be...

Epstein-Barr virus (EBV) has been strongly linked with African Burkitt’s lymphoma and nasopharyngeal carcinoma (NPC) and has recently been associated with breast cancer (1). Nine studies of EBV in breast cancer with the use of different methods (1–9) present conflicting results. In the current study, microdissected ductal breast carcinomas were tested for EBV. Only one of 115 cases was positive...

V. P E NG O ,* A . TR IP OD I , G. R EBER , J . H . RAND,§ T . L . ORTEL ,– M. GALL I ** and P . G . DE GROOT *Clinical Cardiology, Thrombosis Center, University Hospital, Padova; Angelo Bianchi Bonomi Haemophilia and Thrombosis Centre, University and IRCCS Maggiore Hospital, Mangiagalli and Regina Elena Foundation, Milan, Italy; Haemostasis Unit, Division of Angiology and Haemostasis, Universi...

Background: Gamma heavy chain disease (GHCD) is a rare B-cell neoplasm that produces truncated lacks light chain-binding sites.1 Angioimmunoblastic T-cell lymphoma (AITL) associated with EBV driven lymphoproliferative disease,2 and EBV-independent plasma clonal cell expansion,3 but concurrence both has not been described. Case presentation: An 81-year-old female presented adenopathy, dysphagia ...

CT: computed tomography EBER-ISH: Epstein-Barr viruseencoded RNA in situ hybridization EBV: Epstein-Barr virus LYG: lymphomatoid granulomatosis INTRODUCTION Lymphomatoid granulomatosis (LYG) is a rare B-cell lymphoproliferative disorder that involves the skin in approximately 50% of cases. We describe a patient with LYG who first presented with cutaneous lesions. His skin biopsy failed to show ...

We extend the definition of coherent risk measures, as introduced by Artzner, Delbaen, Eber and Heath, to general probability spaces and we show how to define such measures on the space of all random variables. We also give examples that relates the theory of coherent risk measures to game theory and to distorted probability measures. The mathematics are based on the characterisation of closed ...

Nasopharyngeal carcinoma (NPC) is rare among people of Indian ethnicity. A short retrospective case review of clinical records of Indian patients diagnosed with nasopharyngeal carcinoma in a period of 5 years was conducted. Their slides were further subjected to EBV encoded RNA (EBER) - In- situ Hybridization (ISH). The histologic subtype was nonkeratinizing carcinoma in all 4 patients. All wer...