Solving linear systems is an important problem for scientific computing. Exploiting parallelism is essential for solving complex systems, and this traditionally involves writing parallel algorithms on top of a library such as MPI. The SPIKE family of algorithms is one well-known example of a parallel solver for linear systems. The Hierarchically Tiled Array data type extends traditional data-pa...

background: health technology assessment (hta) is a tool utilized for efficient dissemination of technology. for the purpose of encouraging decision-makers to utilize this tool, at first, we need to identify the obstacles in the processes of preparation, utilization, and implementation of htas. this study aims to define these barriers and offer solutions for effective utilization of hta reports...

The Arabidopsis thaliana histone H2A gene HTA1 is essential for efficient transformation of Arabidopsis roots by Agrobacterium tumefaciens. Disruption of this gene in the rat5 mutant results in decreased transformation. In Arabidopsis, histone H2A proteins are encoded by a 13-member gene family. RNA encoded by these genes accumulates to differing levels in roots and whole plants; HTA1 transcrip...

OBJECTIVES The aim of this work was to provide a comprehensive overview of the evolution of the health technology assessment (HTA) concept in the scientific literature through a scientometric approach. METHODS A literature search was conducted, by selecting publications, as well as news from the media, containing "health technology assessment" in their title, abstracts, or keywords. We then u...

There is a high early death rate in patients with myeloma with the single biggest cause being infection. Antibiotic prophylaxis is likely to be the most effective measure to prevent early death in this patient population. TEAMM is a randomised, double-blind, placebocontrolled multi-centre phase III clinical trial seeking to tackle early morbidity and mortality in patients with myeloma by assess...

Orphan drugs (ODs) are intended for the diagnosis, prevention, or treatment of rare diseases. Many cancer subtypes, including all childhood cancers, are defined as rare diseases, and over one-third of ODs are now intended to treat oncology indications. However, market access for oncology ODs is becoming increasingly challenging; ODs are prone to significant uncertainty around their cost-effecti...

The first steps towards Health Technology Assessment (HTA) were taken in Romania between 1992-2002 when some form of mentorship was performed in this area with Canadian support [1]; later on, from 2002 to 2011 HTA remained a subject only for the academic and research purposes. Only the pressure brought by the Memorandum of Understanding between Romanian Government with International Monetary Fu...

This research was conducted to organize and model a comprehensive paratransit dispatching task activity in a computer-assisted control room. The dispatching task involves continuous monitoring and interaction with archived and real-time data using a dispatch software. Extensive field observations and video recordings of dispatch operations were conducted. Then, an expert dispatcher was used to ...

One of the main purposes of conducting a health technology assessment (HTA) is to provide decision makers, patients, related researchers (e.g., in the areas of health policy, HTA, or health technology development), and reimbursement payers with information about the economic, organizational, social, and ethical impacts of specific health technologies, as well as obtaining clinical evidence and ...

Also, a fully searchable CD-ROM containing the full text of all HTA monographs is available from the NCCHTA offices or via the HTA website. The CD-ROM is updated with the most recently published monographs every 6 months and is available free of charge to postal addresses in the UK. In addition, printed paper copies of this report may be obtained by writing to: The website also provides informa...