The LHC beam dump extraction kicker system consists per ring of 15 magnets and their pulse generators. Their task is to extract the beams on request, over the whole operational beam energy range and synchronously with the beam abort gap. This operation must be fail-safe to avoid damage to accelerator equipment by undesired beam losses. The control system of the LHC beam dump kickers will be bas...

L-nucleoside analogues such as lamivudine are active for treating viral infections. Like D-nucleosides, the biological activity of the L-enantiomers requires their stepwise phosphorylation by cellular or viral kinases to give the triphosphate. The enantioselectivity of NMP kinases has not been thoroughly studied, unlike that of deoxyribonucleoside kinases. We have therefore investigated the cap...

Land cover classification with a high accuracy is necessary, especially in waste dump area, accurate land cover information is very important to eco-environment research, vegetation condition study and soil recovery destination. Funded by the international cooperation project Novel Indicator Technologies for Minesite Rehabilitation and sustainable development, a hierarchical object oriented lan...

The morphological structure of turfs and the activity main enzymes antioxidant protection: peroxidase, superoxide dismutase (SOD) catalase dominant species mosses Barbula unguiculata Hedw,, Bryum caespiticium Hedw., argenteum Hedw. Brachythecium salebrosum (Hoffm. eх F.Weber & D. Mohr) Schimp. from different transects northern exposure sulfur mining dump No. 1 in summer autumn seasons were ...

Timing and duration of pre-meiotic G1, S and G2 phases in Paramecium caudatum have been clarified by microspectrophotometry of DNA content and autoradiography with [3H]thymidine ([3H]dThd) and [3H]deoxyuridinemonophosphate ([3H]dUMP). Microspectrophotometric measurement of DNA content showed that cells in stationary phase have a G1 micronucleus, and that pre-meiotic DNA synthesis begins with th...

Protein p56 encoded by the Bacillus subtilis phage phi29 inhibits host uracil-DNA glycosylase (UDG) activity. In previous studies, we suggested that this inhibition is likely a defense mechanism developed by phage phi29 to prevent the action of UDG if uracilation occurs in DNA either from deamination of cytosine or the incorporation of dUMP during viral DNA replication. In this work, we analyze...

We have previously reported the presence, in the parasitic protozoan Leishmania major, of an enzyme involved in controlling intracellular dUTP levels. The gene encoding this enzyme has now been overexpressed in Escherichia coli, and the recombinant enzyme was purified to homogeneity. Biochemical and enzymic analyses of the Leishmania enzyme show that it is a novel nucleotidohydrolase highly spe...

Proteorhodopsin (pR) is a membrane-embedded proton pump from the microbial rhodopsin family. Light absorption by its retinal chromophore initiates a photocycle, driven by trans/cis isomerization on the femtosecond to picosecond time scales. Here, we report a study on the photoisomerization dynamics of the retinal chromophore of pR, using dispersed ultrafast pump-dump-probe spectroscopy. The app...