An amphiphilic phosphodiester-linked azobenzene trimer has been exploited in the development of stimuli-responsive, water-soluble supramolecular polymers. The can reversibly undergo thermal and photoisomerization between Z- E-isomers. Its self-assembly properties aqueous medium have investigated by spectroscopic microscopic techniques, demonstrating that E- Z-azobenzene trimers form nanosheets ...

The development of dual-imaging enabled cancer-targeting nanoparticles (DICT-NPs) is reported based on newly developed biodegradable photoluminescent polymers and superparamagnetic iron oxide nanoparticles. DICT-NPs possess capabilities of dual-imaging (magnetic resonance imaging and optical imaging), magnetic targeting, and potentially selective targeting for cancer cells. The development of D...

Abstract Drug delivery systems and thermoresponsive polymers are garnering more interest due to technological advancement. The synthesis, characteristics, uses of stimuli-responsive in drug discussed this paper. LCST UCST polymers, two subtypes also discussed, along with their processes biomedical applications. paper discusses the use conventional nanofibers for most recent developments electro...

Polymeric gene-delivery vectors to achieve lack of toxicity and a balance between protection and DNA release remains a formidable challenge. Incorporating intracellular environment-responsive degradable bonds is an appreciable step toward developing safer transfection agents. In this study, novel, dual-degradable polycation copolymers (Pluronic-diacrylate [PA]-polyethyleneimine [PEI]-SS) were s...

Polylactic acid (PLA) has found widespread use in plastics and in biomedical applications due to its biodegradability into natural benign products. However, PLA-based materials remain limited in usefulness due to difficulty of incorporating functional groups into the polymer backbone. In this paper, we report a strategy for PLA functionalization that establishes the preparation of highly deriva...

The effect of atrial contraction on cardiac function is reviewed in patients with dual chamber and rate-responsive ventricular pacemakers. The question posed was is there any haemodynamic, clinical or prognostic advantage of AV synchrony in dual chamber pacemakers in comparison to rate-responsive ventricular pacemakers? Optimal AV delay in dual chamber pacing favours cardiac performance at rest...