Expression profiles of primary breast tumors were investigated in relation to disseminated tumor cells (DTCs) in bone marrow (BM) in order to increase our understanding of the dissemination process. Tumors were classified into five pre-defined molecular subtypes, and presence of DTC identified (at median 85 months follow-up) a subgroup of luminal A patients with particular poor outcome (p=0.008...

OBJECTIVE Greater intake of Cruciferous vegetables (e.g. broccoli) may prevent cancer at several sites. Urinary excretion of isothiocyanate conjugates (dithiocarbamates, DTC) provides a specific biomarker of Cruciferous vegetable consumption suitable for epidemiological investigations. However, no gold-standard referent is available for evaluating urinary DTC levels as an estimator of Crucifero...

As differentiated (follicular and papillary) thyroid cancer (DTC) may recur years after initial treatment, follow-up of patients with DTC is long term. However, this population has changed, with more individuals being discovered at an earlier stage of disease, so that previous follow-up protocols based mostly on data from high-risk patients no longer apply. We have proposed, in a previous issue...

The development of distant metastases is the major cause of death from breast cancer. In order to predict and prevent tumour spreading, many attempts are being made to detect small numbers of tumour cells that have shed from the primary lesions and have moved to lymph nodes, blood or bone marrow. This article presents the advantages and the limitations of techniques used for disseminated tumour...

This paper presents the analysis and simulation of the control of double star induction motor, using direct torque control (DTC) based on model reference adaptive control algorithm (MRAC). The DTC is an excellent solution for generalpurpose induction drives in very wide range the short sampling time required by the TC schemes makes them suited to a very fast torque and flux controlled drives as...

The growth in direct-to-consumer advertising(DTCA)over the past two decades has facilitated the communication of prescription drug information directly to consumers. Data from a 1999 national survey are employed to determine the factors influencing consumers' opinions of the utility of DTC ads for health care decision making. We also analyze whether consumers use DTC ad information in health ca...

We present a two-part system for conditional FLP-out of FRT-flanked sequences in Caenorhabditis elegans to control gene activity in a spatially and/or temporally regulated manner. Using reporters, we assess the system for efficacy and demonstrate its use as a cell lineage marking tool. In addition, we construct and test a dominant-negative form of hlh-12, a gene that encodes a basic helix-loop-...

WILSON, J. R. AND L. V. DICARA. Effects of previous curare-immobilization on Pavlovian conditioned heart rate decelerations in the curarized rat. PHYSIOL. BEHAV. 14(3) 259-264, 1975. Recent evidence indicates that mechanisms other than the vagal-blocking properties of d-tubocurarine chloride (dTC) or inadequate respiration may account for the reports of invariant heart rate (HR) in curarized ra...

BACKGROUND Cervical lymph node metastases from differentiated thyroid cancer (DTC) are common. Thirty to eighty percent of patients with papillary thyroid cancer harbor lymph node metastases, with the central neck being the most common compartment involved. The goals of this study were to: (1) identify appropriate methods for determining metastatic DTC in the lateral neck and (2) address the ex...

In this paper, a new adaptive reference based approach to direct torque control (DTC) method has been proposed for brushless direct current (BLDC) motor drives. Conventional DTC method uses two main reference parameters as: flux and torque. A main difference from the conventional method of it was that only one reference parameter (speed) was used to control the BLDC motor and the second control...