نتایج جستجو برای: dta tga
تعداد نتایج: 8405 فیلتر نتایج به سال:
Mast cells have been implicated in malignant processes, mainly through clinical correlative studies and by experiments performed using animals lacking mast cells due to defective c-kit signaling. However, mast cell-deficient mouse models based on c-kit defects have recently been questioned for their relevance. Here we addressed the effect of mast cells in a tumor setting by using transgenic Mcp...
AIM To assess the ability of human immunodeficiency virus-1 (HIV-1) tat- and tat/nef-defective genomes containing diphtheria toxin A chain gene (DTA) to inhibit replication of HIV in human cells. METHODS Plasmids were constructed to contain the HIV-1 genome disabled by tat and tat/nef deletions, and sequences coding for the A subunit of diphtheria toxin gene were inserted into one of these de...
This paper presents an improved diagonal tensor approximation (DTA) and its hybridization with the stabilized biconjugate-gradient fast Fourier transform (BCGS–FFT) algorithm to solve a volume integral equation for three-dimensional (3D) objects in layered media. The improvement in DTA is obtained for lossy media through a higher-order approximation. The interaction between the dyadic Green’s f...
To obtain single crystals by solution growth, an exposed primary solidification surface in the appropriate, but often unknown, equilibrium alloy phase diagram is required. Furthermore, an appropriate crucible material is needed, necessary to hold the molten alloy during growth, without being attacked by it. Recently, we have used the comparison of realistic simulations with experimental differe...
Dynamic Traffic Assignment (DTA) has been studied for more than four decades and numerous reviews of this research area have been conducted. This review focuses on the travel choice principle and the model classifications of DTA, and is supplementary to the existing reviews. The implications of the travel choice principle for the existence and uniqueness of solutions of DTA are discussed, and t...
Immunotherapy for cancer using antibodies to enhance T-cell function has been successful in recent clinical trials. Many molecules that improve activation and effector function of T cells have been investigated as potential new targets for immunomodulatory antibodies, including the tumor necrosis factor receptor superfamily members GITR and OX40. Antibodies engaging GITR or OX40 result in signi...
To obtain rates of mRNA synthesis and decay in yeast, we established dynamic transcriptome analysis (DTA). DTA combines non-perturbing metabolic RNA labeling with dynamic kinetic modeling. DTA reveals that most mRNA synthesis rates are around several transcripts per cell and cell cycle, and most mRNA half-lives range around a median of 11 min. DTA can monitor the cellular response to osmotic st...
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