The previous two standard operating procedures (SOPs) related to the culture and drug susceptibility testing (DST) of Mycobacterium tuberculosis with the microscopic observation drug susceptibility assay (Part 1) and nitrate reductase assay (Part 2). The present SOP is devoted to a third non-commercial culture and DST method known as colorimetric redox indicator assay (CRI). As its name indicat...

A two-element protocol consisting of one donor-specific transfusion (DST) plus a brief course of anti-CD154 mAb greatly prolongs the survival of murine islet, skin, and cardiac allografts. To study the mechanism of allograft survival, we determined the fate of tracer populations of alloreactive transgenic CD8+ T cells in a normal microenvironment. We observed that DST plus anti-CD154 mAb prolon...

and Music. Talk given at PoRT workshop, Glasgow, July 2012 Fred Cummins, University College Dublin [1] Dynamical Systems Theory (DST) is the lingua franca of Physics (both Newtonian and modern), Biology, Chemistry, and many other sciences and non-sciences, such as Economics. To employ the tools of DST is to take an explanatory stance with respect to observed phenomena. DST is thus not just anot...

The principal reason for introducing (and extending) daylight saving time (DST) was, and still is, projected energy savings, particularly for electric lighting. This paper presents a literature review concerning the effects of DST on energy use. Simple estimates suggest a reduction in national electricity use of around 0.5%, as a result of residential lighting reduction. Several studies have de...

SETTING One reference and three zonal laboratories and 500 health facilities managing retreatment tuberculosis (TB) patients in Tanzania. OBJECTIVES The National Tuberculosis and Leprosy Programme (NTLP) requires that all notified cases of retreatment TB in Tanzania have sputum samples sent for culture and drug susceptibility testing (DST). This study determined 1) if the number of annually n...

OBJECTIVE The objective of this study was to evaluate the effects of the decision support tool (DST) on the assessment of the acutely ill or injured out-of-hospital patient. METHODS This study included systematic reviews of randomized controlled trials (RCT) where the DST was compared to usual care in and out of the hospital setting. The databases scanned include: (1) Cochrane Reviews (up to ...

This paper presents an integrated approach which utilizes multi criteria decision making (MCDM) alongside with Dempster Shafer Theory of evidence (DST) for the selection of landfill sites. It employs a two stage analysis for selecting landfill sites in urban region of Zanjan. The first-stage analysis makes use of the maps in Geospatial information system (GIS) in conjunction with different vari...

Academic and social success in school has been linked to children’s self-regulation. This study investigated the assessment of the executive function (EF) component of self-regulation using a low-cost, easily administered measure to determine whether scores obtained from the behavioral task would agree with those obtained using a laboratory-based neuropsychological measure of EF skills. The sam...

NMR spectroscopy combined with molecular modeling was used to characterize a heterodimeric complex with Dst and 2-ImN bound in the minor groove of d(GCCTAACAAGG).d(CCTTGTTAGGC) (1:1:1 2-ImN.Dst.DNA complex). The imidazole-pyrrole-pyrrole ligand 2-ImN spans 5'-GTTA-3' of the TAACA.TGTTA binding site with the imidazole nitrogen specifically recognizing the guanine amino group. The Dst ligand lies...

BACKGROUND Individualized treatment for multidrug-resistant (MDR) tuberculosis and extensively drug-resistant (XDR) tuberculosis depends upon reliable and valid drug susceptibility testing (DST) for pyrazinamide, ethambutol, and second-line tuberculosis drugs. However, the reliability of these tests is uncertain, due to unresolved methodological issues. We estimated the association of DST resul...