Large numbers of patients referred for evaluation of chest pain are unable to perform adequate, diagnostic exercise testing. In these patients, dobutamine stress echocardiography (DSE) represents an alternative, exercise-independent stress modality. Apart from the approximately 5% of patients with an inadequate acoustic window, 10% of patients referred for this test have nondiagnostic (submaxim...

BACKGROUND Normal left anterior descending (LAD) coronary artery as determined by coronary angiography is considered not only to reflect normal angiography but also to correlate with normal anatomy and function. However, subjects who undergo coronary angiography may differ from those who do not need to have invasive evaluation even if their functional noninvasive studies like dobutamine stress ...

Introduction This work describes, for the first time, a process for optimising both the standard Stejskal–Tanner (ST) diffusion MR sequence and the dual spin-echo (DSE) sequence, for the specific purpose of directly estimating axon radius or other microstructural properties of white matter. There has been considerable recent interest in the use of diffusion MR for this purpose (e.g. [1,2]). A c...

OBJECTIVES The aim of this project was to assess the utility of dobutamine stress echocardiography (DSE) for evaluation of women with suspected ischemic heart disease. BACKGROUND Most investigations addressing efficacy of diagnosis and treatment of coronary artery disease (CAD) have been performed in predominantly male populations. As part of the Women's Ischemia Syndrome Evaluation (WISE) st...

BACKGROUND Non-diagnostic dobutamine stress echocardiography (ndDSE, failure to achieve 85% of maximal predicted heart rate (HR) without evidence of inducible ischemia) is an important limitation affecting quality of DSE testing. The objectives of this study were to identify the clinical variables associated with a non-diagnostic Dobutamine Stress Echocardiogram (ndDSE) and further evaluate the...

INTRODUCTION Microcirculation dysfunction is a typical feature of systemic sclerosis (SSc) and represents the earliest abnormality of primary myocardial involvement. We assessed coronary microcirculation status by combining two functional tests in SSc patients and estimating its impact on disease outcome. METHODS Forty-one SSc patients, asymptomatic for coronary artery disease, were tested fo...

We present results from a study of subtractive renormalization of the fermion propagator Dyson-Schwinger equation (DSE) in massive strongcoupling quenched QED4. Results are compared for three different fermionphoton proper vertex Ansätze: bare γ, minimal Ball-Chiu, and CurtisPennington. The procedure is straightforward to implement and numerically stable. This is the first study in which this t...

Many problems in distributed software engineering (DSE) arise, because the participants of a team are not trained in DSE. We present an integrated development environment which supports collaborative working. To introduce such a system in the teaching of software engineering provides for a higher educational standard and for a better awareness of students for the problems involved in distribute...

BACKGROUND Exercise-induced hypertension following repair of the coarctation of the aorta (CoA) is a well known phenomenon. The most important functional parameters in the assessment of the effects of a surgical repair of CoA are the maximal pressure gradient in the descending aorta (GRAD) and systolic blood pressure (SBP). Results of treadmill exercise test using the Bruce protocol (treadmill ...

Cisplatin causes auditory impairment due to the apoptosis of auditory hair cells. There is no strategy to regulate ototoxicity by cisplatin thus far. Dansam-Eum (DSE) has been used for treating the central nerve system injury including hearing loss in Korea. However, disease-related scientific investigation by DSE has not been elucidated. Here, we demonstrated that DSE and its component rosmari...