Down sydrome (DS) is a relatively frequent chromosomal disorder, which has no safe and effective method of prenatal diagnosis to date. The present study was designed to identify DS biomarkers. We quantified the changes in the umbilical cord blood protein levels between DS-affected and healthy (control) pregnant females using isobaric tags for relative and absolute quantification (iTRAQ) and Gen...

BACKGROUND The use of dietary supplements (DS) is common among persons with dementia. Direct risks associated with DS use include adverse events and DS-drug interactions. A direct risk is a risk caused by the treatment itself. Indirect risks are related to the treatment setting, such as the conditions of use, and not to the treatment itself. Because dementia symptoms may reduce a person's abili...

INTRODUCTION "Obesity" is considered a feature of youth with DS but whether "low physical fitness" is also a feature is unknown. OBJECTIVE The aim of this case-control study was to compare the levels of fatness and fitness in adolescents with and without DS. METHODS Participants included 17 (5 girls) adolescents with DS aged 12-18 years and a control group of 94 (45 girls) adolescents witho...

OBJECTIVE To assess the nutritional status and prevalence of obesity among children with Down syndrome (DS). METHODS The study group comprised pre-pubertal children, with clinically and cytogenetically proven DS. Healthy siblings, closest in age to the DS children, were used as a control group. Body weight, height, body mass index (BMI), triceps skinfold thickness (TSFT), and macro- and micro...

This study deals with sentence patterns, including quoted verses of the Quran in Kissa-i Musa. The positions quotations can be classified as intrasentential and intersentential this text. While an quotation indicates a complete Turkish sentence, on other hand, is part sentence. Moreover, are combined or without conjunction ki kim sentences. mainly aims to find how were placed For reason, senten...

Information on the determinants of dietary supplement (DS) use in France is largely lacking, especially in population subgroups such as smokers. Also, little is known about the role of health professionals in DS purchases. The aim of the present study was to describe DS use along with its sociodemographic, lifestyle and dietary correlates in a large sample of French adults (age 18+years) partic...

The aim of this study was to evaluate the influence of endogenous nitric oxide on resting microvascular tone in the Dahl salt-sensitive (DS) rat and to determine how this influence is altered in salt-induced hypertension. Intravital microscopy was used to examine the arteriolar network in the spinotrapezius muscle of DS rats maintained on low (0.45% NaCl) or high (4% NaCl) salt diets for 6-7 we...

A Gram-negative, non-motile, pale-yellow, rod-shaped bacterial strain, DS-42(T), was isolated from a soil in Korea and its taxonomic position was investigated by a polyphasic study. Strain DS-42(T) grew optimally at 25 degrees C and pH 7.0-8.0. Strain DS-42(T) did not form nodules on three different legumes, and the nodD and nifH genes were also not detected by PCR. Strain DS-42(T) contained Q-...

Previous studies have indicated that LLA-DR homozygous cell lines express two DR molecules but only a single DS (I-A-like) molecule. This report demonstrates that an HLA-DR5 homozygous cell line expresses at least two distinct DS molecules. These two DS molecules are formed by the association of a single DS alpha chain with either of two DS beta chains. Four distinct Ia molecules have now been ...

down's syndrome (ds) is the most common chromosomal abnormality in human. subjects with ds are known to be peridisposed to develop leukemia. the molecular basis of the association between ds and leukemia is unknown. the unscheduled dna synthesis (uds) test measure the ability of dna-repair in mammalian cells after excision of a stretch of dna containing the region of damage induced by chem...