OBJECTIVES To use primary care electronic health records (EHRs) to evaluate prescriptions and inappropriate prescribing in men and women at age 100. DESIGN Population-based cohort study. SETTING Primary care database in the United Kingdom, 1990 to 2013. PARTICIPANTS Individuals reaching the age of 100 between 1990 and 2013 (N = 11,084; n = 8,982 women, n = 2,102 men). MEASUREMENTS Main ...

Cyclooxygenase (COX)-2-specific inhibitors were developed to circumvent the gastrointestinal toxicity of non-specific non-steroidal anti-inflammatory drugs while maintaining efficacy. However, the higher acquisition cost of COX-2-specific inhibitors has resulted in the implementation of a programme for cost containment in the Ontario public drug program. This programme consists of limited use (...

Schizophrenia is a chronic debilitating major psychiatric disorder which may require life long treatment. Treatment of such patients at an early stage may prevent loss of morbidity, mortality and productivity. Till date, pharmacotherapy remains the cornerstone of treatment in such patients . Serendipitous discovery of chlorpromazine and lithium in the fifties brought about a revolution in the f...

The objective of this study was to determine the prevalence of Potentially Inappropriate Medication (PIM) use and associated factors, as well as the prevalence of Prescribing Omissions (PO). A cross-sectional study was conducted in a philanthropic Brazilian nursing home involving 46 individuals aged 60 years or older. The following information was collected from medical records and drug prescri...

other preventive and promotive services. A medicine kit is provided to them every 6 month (Appendix)(2). However, non-availability of drugs is often reported by AWWs, and concern has also been expressed about the possibility of improper drug use by them(3). This study was planned with the objective to find out the availability of drugs in Anganwadis, the knowledge of AWWs about drug usage, and ...

Drug Utilization Evaluation (DUE) studies are designed to assess drug usage appropriateness. We aim to evaluate the drug utilization of intravenous ciprofloxacin and imipenem, two of the broad spectrum antibiotics that consume a significant proportion of our hospitals’ outlay, in different wards of a teaching hospital in Zabol. During a 5 months period (December 2010 to May 2011), 263 patients ...