the paper deals with the analysis of the external factor (solar activity, volcanic eruptions) influence on tree growth at the kola peninsula, northwestern russia. pinus sylvestris l. (scots pine) tree-ring chronologies collected nearby the northern timberline (68.63n, 33.25e) include the oldest (1445-2005 ad) living pine tree found up to date in the kola peninsula. a total of 18 living trees p...

PD-1: Programmed death receptor

We report on a rare case of fluconazole induced fixed drug eruption in a 62-year old female patient. She was referred to our department for multiple erythematous itchy maculopatches on the face, neck, both upper arms, and trunk area, which had occurred over the previous 6 months. Her attending physician prescribed fluconazole for treatment of onychomycosis. Patch test and oral provocation were ...

TNPM presents as subcorneal or intraepidermal pustules composed mainly of neutrophils; this finding helps to differentiate TNPM from NTE, in which there is a predominance of eosinophils. In conclusion, we must be aware that TNPM is a benign condition with no systemic manifestations and it does not require treatment. This entity can be confused with serious infections, and patients with TNPM may...