نتایج جستجو برای: drug donors
تعداد نتایج: 624886 فیلتر نتایج به سال:
PurposeWith the expansion of donor pool through Hepatitis C viremic donors (HCV+), use DAA agents for treatment and prophylaxis has expanded in cardiothoracic transplant (CTT). Azole antifungal (AAF) is common CTT to prevent systemic fungal infections, several drug interactions (DDI) such as PGP inhibition. Glecaprevir/pibrentasvir (GP) a agent used HCV+ donors, utilizing pathway. While availab...
: iron supplementation for blood donors is a controversial concept. however, to maintain regular blood donors, as a source of blood supply, the present paradigm is not appropriate and dose not prevent harms to blood donors. methods: a randomized, double-masked, placebo-controlled study, was conducted by enrolling 95 female regular blood donors of childbearing age (18-49 years). the participan...
Autoimmune diseases currently take a leading place in terms of frequency occurrence the population, among which 1 percent is occupied by rheumatoid arthritis (RA). Remission this type disease extremely rare and requires constant use pharmacotherapy. Studying pathogenesis RA necessary to study search for new drug targets. It known that T helpers (Th) Th17 are involved development RA. However, so...
here, we report analysis of in vitro and in vivo drug release from an in situ formulation consisting of triamcinolone acetonide (tr) and poly(d,l-lactide-co-glycolide) (plga) and the additives glycofurol and hydroxyapatite nanoparticles (ha). we found that these additives enhanced drug release rate. we used the taguchi method to predict optimum formulation variables to minimise the initial burs...
Evaluation of trends in the rate of infectious diseases of blood donors is essential for monitoring safety of blood supply and effective screening of donors. Transfusion records of blood donors who attended the Center between 2002 and 2005 were reviewed for positive cases of HBS (by ELISA), HIV (by Western Blot) and HCV (by ELISA). During 2002–05, 507,531 persons donated blood. The prevalence r...
Histone deacetylase inhibitors have gained a great deal of attention recently for the treatment of cancers and inflammatory diseases. So design of new inhibitors is of great importance in pharmaceutical industries and labs. Creating pharmacophor models in order to design new molecules or search a library for finding lead compounds is of great interest. This approach reduces the overall cost ass...
Organ transplantation in Iran like many other countries is accepted as the last therapeutic method for patients with end-stage organ failure. Sources of transplantable organs include living and deceased/brain dead donors, among which a considerable number of organs for transplant are obtained from living donors. Removal of organs from deceased and brain dead donors for transplantation is allowe...
Introduction: Blood derived products have been known as an effective treatment for many years. However, this treatment is not without risk of infections transmission including hepatitis B virus (HBV) and hepatitis C virus (HCV) and human immune-deficiency virus (HIV) in people who received the blood. Nevertheless, due to a high risk of blood born diseases through blood transfusion, screening ...
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