نتایج جستجو برای: drug carriers
تعداد نتایج: 628741 فیلتر نتایج به سال:
STUDY OBJECTIVES To determine whether inactive hepatitis B surface antigen (HBsAg) carriers are at a higher risk of drug-induced hepatotoxicity than control subjects during antituberculosis treatment with standard short-course regimens of isoniazid, rifampin, ethambutol, and/or pyrazinamide. DESIGN Retrospective case-control study. SETTING Tertiary university medical center. PATIENTS One ...
Abstract The lipid-based colloidal carriers, such as nanostructured lipid carriers (NLCs), solid nanoparticles (SLNs), nanocapsules, liposomes, and microemulsion, are the latest significant entrants in development of drug delivery systems owing to their myriad advantages. NLCs second-generation SLNs having unstructured matrix, have high loading, provide long-term stability comparison other syst...
Background: The aim of this study was to investigate interaction between vanillin and alpha-, beta- and gamma-cyclodextrin carriers for targeted drug delivery and compare the performance between them using theoretical methods. Methods: All theoretical calculations were performed on a Intel® Core™ i5 Processors computer at Kerman University using Gaussian 09 program package (Gaussian, Inc., Wal...
A DNA tetrahedron is employed for efficient delivery of doxorubicin into drug-resistant breast cancer cells. The drug delivered with the DNA nanoconstruct is considerably cytotoxic, whereas free doxorubicin is virtually non-cytotoxic for the drug-resistant cells. Thus, the DNA tetrahedron, made of the inherently natural and biocompatible material, can be a good candidate for the drug carrier to...
Nanoscale carriers are of increasing interest for use in anticancer therapy because they can deliver drugs in a targeted way. Ideally, nanocarriers combine passive and active delivery mechanisms, by integrating targeting ligands on the surface of their stealth corona using simple and efficient conjugation chemistry. This feature article summarizes the conventional and newly explored conjugation...
Lipid-based innovations have achieved new heights during the last few years as an essential component of drug development. The current challenge of drug delivery is liberation of drug agents at the right time in a safe and reproducible manner to a specific target site. A number of novel drug delivery systems has emerged encompassing various routes of administration, to achieve controlled and ta...
Biocompatible PEO-b-PCL Nanosized Micelles as Drug Carriers: Structure and Drug–Polymer Interactions
Physical and mechanical properties of the drug-incorporated polymer play a significant role in release behavior from drug carriers. Understanding relative extent variation physical makes it possible to improve design carriers obtain better profile increase stability. Drug delivery PLGA loaded with various percentages diclofenac sodium (DS: 0, 5%, 10%) at different flow rates 0 7.5 ml/s (flow ra...
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