Chair and Department of General, Gastroenterological and Endocrine Surgery, K. Marcinkowski Medical University in Poznań1 Kierownik: prof. dr hab. M. Drews Chair and Department of General and Endocrine Surgery, K. Marcinkowski Medical University in Poznań2 Kierownik: dr hab. P. Krokowicz Chair and Department of Pediatric Gastroenterology and Metabolic Diseases, K. Marcinkowski Medical Universit...

I have received your letter dated December 1 2000, concerning the rejection of my manuscript which was submitted for publication in .... . I understand that the enclosed reviews are highly unfavorable and as an editor you were left with little choice but to reject the manuscript. I believe that the criticism of the reviewers, which are almost hostile towards the ideas I have advocated, are larg...

Background Over the past few decades diabetes has emerged as an important non-communicable disease in SubSaharan Africa (SSA). Sight loss from Diabetic Retinopathy (DR) can be prevented with screening and early treatment. The objective of this paper is to outline the required actions and considerations in the planning and development of DR screening services.   Methods A multiple-case study app...

PURPOSE The development of local and distant recurrences is a major problem in the treatment of rectal cancer patients. In this study, we investigated whether epithelial human leukocyte antigen-DR (HLA-DR) expression allowed discrimination between high and low tumor recurrence rates, and analyzed the mechanism behind its expression. EXPERIMENTAL DESIGN The role of IFNgamma in HLA-DR expressio...

AIM To examine the possible influence of the MHC class II antigens alleles in the formation of the multinucleate aggressive giant cell tumour of bone. METHODS HLA class II antigen alleles were investigated in eight white patients from north east England with confirmed diagnosis of giant cell tumour of bone. All had locally aggressive, immunophenotypically HLA-DR negative giant cell tumours. ...

BACKGROUND The role of HLA-DR antigens in the clinicopathological features of autoimmune hepatitis (AIH) is not clearly understood. We examined the implications of HLA-DR antigens in Japanese AIH, including the effect of HLA-DR4 on the age and pattern of AIH onset, clinicopathological features, and treatment efficacy. METHODS A total of 132 AIH patients consecutively diagnosed and treated in ...

Background: It has been believed that diabetic retinopathy (DR) is a microvascular disorder. Recent research linked DR to both neuronal and processes. The purpose of this was use optical coherence tomography angiography (OCTA) compare the thickness peripapillary area retinal nerve fiber layer (pRNFL) in different stages.Methods: This cross-sectional controlled carried out on 40 subjects Cases w...