نتایج جستجو برای: dotap nanoliposome
تعداد نتایج: 335 فیلتر نتایج به سال:
BACKGROUND Disulfide-linked oligodeoxyribonucleotide (ODN) liposomes were formulated and evaluated for the delivery of antisense ODN G3139 in KB human oral carcinoma cells. MATERIALS AND METHODS Liposomes composed of 1,2-di-(9Z-octadecenoyl)-3-trimethylammo-nium-propane (DOTAP)/egg phosphatidylcholine/alpha-tocopheryl polyethylene glycol 1000 succinate were incorporated with hydrophobized dis...
This study is focused on the effect of phycobiliprotein extraction Gracilaria quality common carp burgers, and application nanoliposomes containing pigment in improvement its antimicrobial antioxidant activity burgers during refrigerated storage 18 days. Burgers were incorporated with liposomal (2.5% 5% w/w), their chemical microbial changes terms pH, peroxide value (PV), thiobarbituric acid (T...
The mechanisms through which melatonin exerts its inhibitory effect on cell death remains insufficiently clarified. The subject of the present study is the evaluation of the hepatoprotective effects of melatonin on the inhibition of apoptotic and oxidative processes and activation of survival pathways, in comparison with betaine, in a primary culture of hepatocytes that have undergone Fas-ligan...
Ceramide is a sphingolipid metabolite that induces cancer cell death. When C6-ceramide is encapsulated in a nanoliposome bilayer formulation, cell death is selectively induced in tumor models. However, the mechanism underlying this selectivity is unknown. As most tumors exhibit a preferential switch to glycolysis, as described in the "Warburg effect", we hypothesize that ceramide nanoliposomes ...
Creation of novel and smart materials is one of the driving forces for the evolution of coating and encapsulation technologies. A challenge of materials engineering is the controlled assembly of purposefully designed molecules, or ensembles of molecules, into nanoand micrometer-scale structures to provide increasingly precise control at molecular levels, over the structure, properties and funct...
Nanoliposome can be designed as a drug delivery carrier to improve the pharmacological and therapeutic properties of drug administration. (188)Re-labeled nanoliposomes are useful for diagnostic imaging as well as for targeted radionuclide therapy. In this study, the in vivo nuclear imaging, pharmacokinetics and biodistribution of administered nanoliposomes were investigated as drug and radionuc...
Recently, stimuli-responsive drug delivery systems (DDSs) with high spatial/temporal resolution bring many benefits to cancer treatment. However, cancer cells always develop ways to resist and evade treatment, ultimately limit the treatment efficacy of the DDSs. Here, we introduce photo-activated nanoliposomes (PNLs) that impart light-induced cytotoxicity and reversal of drug resistance in sync...
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