PURPOSE To design an efficient method for utilizing phase-space source models in the GPU-based Monte Carlo (MC) dose calculation engine gDPM. METHODS In GPU-based MC algorithms, particles are transported in parallel on different threads. Particles of different types and energies can require significantly different execution times. This can cause "thread divergence" and lower efficiency when s...

BACKGROUND The study summarised in this report aimed to investigate the interplay between fluence complexity, dose calculation algorithms, dose calculation spatial resolution and delivery characteristics (monitor units, effective field width and dose delivery against dose prediction agreement) was investigated. A sample set of complex planning cases was selected and tested using a commercial tr...

The electron Monte Carlo (eMC) dose calculation algorithm of the Eclipse treatment planning system is based heavily upon Monte Carlo simulation of the linac head and modeling of the linac beam characteristics with minimal measurement of beam data. Commissioning of the eMC algorithm on multiple identical linacs provided a unique opportunity to systematically evaluate the algorithm with actual me...

High dose rate brachytherapy has attained the good local control for cervix cancer because radioactive source can be put close to tumors, resulting in increasing the dose delivery per one fraction. However, quality assurance must be accompanied to reduce severe complication. We verified the dose distribution around the source by comparing measured dose with calculated dose by Radiation Therapy ...

PURPOSE To develop a new biological equivalent dose (BED) formulism that includes repair, repopulation and resensitization (redistribution and reoxygenation), and can be used to calculate prescribed dose for permanent implant with Cs-131. METHODS Because of lack of sufficient clinical data, the prescribed dose with new isotopes is usually calculated based on BED compared with other isotopes t...

The objective of this work is to evaluate the interfractional biological effective dose (BED) variation in MammoSite high dose rate (HDR) brachytherapy. Dose distributions of 19 patients who received 34 Gy in 10 fractions were evaluated. A method was employed to account for nonuniform dose distribution in the BED calculation. Furthermore, a range of alpha/beta values was utilized for specific c...

Large quantities of radiopharmaceuticals prescribed for treatment and diagnosis are excreted through kidney. Therefore, radiation unwanted dose is created in kidney. As a result, exact calculation of prescribed radiopharmaceuticals amount is important. Monte Carlo method is used for simulation of radiation transport in body due to random nature of radiation. In this research, for the first time...