OBJECTIVE The aim of the study was to define parameters that influence the initial insulin dosage in young subjects with type 1 diabetes regarding the amount of daily insulin, the ratios of basal and prandial insulin, and the insulin/carbohydrate ratios. STUDY DESIGN We used a computer-based registry (with prospectively collected data) in Germany and Austria, a software for the management and...

Compared with the large body of literature on coping, coping flexibility has received relatively scant research attention, although more such studies have begun to emerge recently. Researchers have conceptualized coping flexibility in diverse ways: as a broad coping repertoire, a well-balanced coping profile, cross-situational variability in strategy deployment, a good strategy-situation fit, o...

background: due (drug utilization evaluation) studies can help identify and correct problems associated with irrational use of drugs. considering lack of data regarding how rational vancomycin is being used, we evaluated this due study in a referral infectious center to evaluate compliance with guidelines in terms of rational use of this valuable antibiotic. methods: this retrospective study wa...

Wheat husks (Fagopyrum esculentum) were modified by treatment with sulfuric acid. The precursor material (FEWS) and the (TFEWS) characterized different techniques to identify structural changes promoted chemical treatment. Subsequently, TFEWS was applied as an adsorbent remove 2,4-dichlorophenoxyacetic acid (2,4-D) pesticide from aqueous solutions. Adsorption studies considered pH effects dosag...

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Measurements of aminoglycoside concentration in serum are used to individualise dosage regimens (dose per administration and/or administration interval) with the goal of attaining the desired therapeutic range as quickly as possible. Therapeutic range is defined in terms of peak concentration (to monitor effectiveness) and trough concentration (to avoid toxicity). This article focuses on method...