in  this  study  we  determined  the  frequency,  sensitivity  and  specificity  of  anti  cyclic citrullinated peptides (anti-ccp) igg antibody, total rheumatoid factor (rf-t), and rf isotypes in iranian patients with rheumatoid arthritis (ra) and their association with age, clinical and serological parameters. anti-ccp and rf-t and rf isotypes level were measured in 418 patients and 399 healt...

background and objectives: coronary artery disease (cad) is regarded as the leading cause of morbidity and mortality around the world. diabetes mellitus (dm) is associated with the development of cad and increased risk of morbidity and mortality. the goal of this study was to assess the association of tumor necrosis factorα (tnf-α) and high sensitivity c-reactive protein (hscrp) with cad severi...

background: in most of the studies, the association of vascular events is limited to migraine with aura or it is stronger in this group, whereas the link between migraine without aura (mo) and vascular events remained uncertain. therefore, we decided to evaluate endothelial function by chemical and functional markers of endothelium in mo and compare with normal population. methods: in this stud...

background selenium deficiency is a common problem in patients with chronic kidney disease (ckd). this micronutrient has anti-inflammatory and anti-oxidant effects. selenium is also found in high concentrations in the thyroid gland. objectives to determine the effect of selenium supplementation on thyroid function tests and acute phase reactants in hemodialysis patients. patients and methods in...

background patients with systemic lupus erythematous (sle) are more prone to atherosclerosis and cardiovascular diseases due to atherosclerosis and consequently death. objectives the aim of this study was to explore a possible relationship between the intima media thickness (imt) of carotid arteries and the levels of c-reactive protein (crp) in sle patients. patients and methods: sixty sle pati...