BACKGROUND The benefits of intravenous tissue-type plasminogen activator (tPA) in acute ischemic stroke are time dependent, and guidelines recommend an arrival to treatment initiation (door-to-needle) time of ≤60 minutes. METHODS AND RESULTS Data from acute ischemic stroke patients treated with tPA within 3 hours of symptom onset in 1082 hospitals participating in the Get With the Guidelines-...

Redundancy reduction of IC models : by multirate time-integration and model order reduction / door Arie Verhoeven.-Dit proefschrift is goedgekeurd door de promotor:

Every year, 90% of Americans give money to charities. Is such generosity necessarily welfare enhancing for the giver? We present a theoretical framework that distinguishes two types of motivation: individuals like to give, for example, due to altruism or warm glow, and individuals would rather not give but dislike saying no, for example, due to social pressure. We design a door-to-door fund-rai...

Communication Door: Real-Time Communication Middleware By Masahiro TABUCHI,* Kazuaki NAKAJIMA,* Akiko KAWAMOTO,* Takashi OSHIBA* and Shujun YOSHIZAKA* We describe a real-time communication middleware system that enables solution providers to construct various applications, such as web conferencing systems and IP-based call centers. The middleware platform, called Communication Door, is a web-ba...

In this paper, we describe our ongoing effort in describing and formalizing semantic relations that link ontologies with each others on the Semantic Web in order to create an ontology, DOOR, to represent, manipulate and reason upon these relations. DOOR is a Descriptive Ontology of Ontology Relations which intends to define relations such as inclusion, versioning, similarity and agreement using...

Most existent door detection methods assume that the panels’ colors are known and rely mainly on this apriori knowledge. However, the color is not always available especially when the environment is entirely unknown. In this paper, a door was defined as a rectangular region with almost a homogeneous color and proper size which one can enter or exit through. The proposed door detection framework...

To improve operations commonly found in today's crossdocks, we offer a door assignment optimization tool that will reduce the distance travelled by goods across the crossdock, as well as workload and labor cost. The cross dock door assignment problem (CDAP) minimizes total distance travelled by the goods inside the crossdock where door capacities are limited by the time they can be used in a wo...

This is the first study to provide national estimates of pediatric door-related injuries in the United States. Data from the National Electronic Injury Surveillance System were analyzed for patients ≤17 years who were treated in US emergency departments for a door-related injury from 1999 through 2008. An estimated 1 392 451 US children ≤17 years received emergency treatment for door-related in...

sepsis constitutes an important cause of hospital admission with a high mortality rate. appropriate antibiotic therapy is the cornerstone of therapy in patients with sepsis. although numerous studies have recommended early antibiotic initiation in severe sepsis or septic shock stages of sepsis syndrome, its role in treatment of patients with sepsis who have not entered these stages remains to b...