To identify the specific biomarkers of exposure DON in chickens, a toxicokinetic study was performed via oral or intravenous application deoxynivalenol (DON). Doses 0.75 and 2.25 mg DON/kg body weight (BW) were administrated intravenously orally to chickens. Next, blood samples collected at several time points plasma obtained. Liquid chromatography–tandem mass-spectrometry (LC–MS/MS) used quant...

In this paper we describe ItLv (Interactive Timeline Viewer), a visualization tool currently used to depict the variants obtained in a textual collation. A textual collation is a process in which a base text is compared against several comparison texts to identify differences (variants) among them. The interactive options of ItLv provide different abstractions of a dataset by enabling the prese...

us believe) in any dialect in Scotland; in fact the tendency in all Scotch dialects is to pronounce it "jest." And as regards the alleged difference of opinion between Mr. Syme and Sir Henry Thompson, I heard Mr. Syme describe his interview with Dickens on the day it took place, and remember that he not only took a serious view of the condition of Dickens' foot, but also spoke of Sir Henry Thom...

For convenience, let us rewrite v(x,y) as a function of three parameters v(dc,don, p): the compressed discontinuity dc, the oriented normalized discontinuity don, and the relative coordinates of the screen-space pixel in the projected light space p. For the parameters dc and p, the description given in the Section 3.1 of the paper is sufficient for this supplementary document. However, we need ...

Abstract The primary objective of this study was to establish a current situation assessment of the possible occurrence of deoxynivalenol in cocoa and cocoa products. Since there was no analytic method for determining DON in cocoa and cocoa products, a special method was developed. The applicability and consistency of the method was confirmed by performing recovery assays on various cocoa produ...

Two of the most common species of toxin-producing Fusarium contaminating small cereal grains are Fusarium graminearum and F. poae; with both elaborating diverse toxins, especially deoxynivalenol (DON) and nivalenol (NIV), respectively. The objective of our work during the 2012-2014 growing seasons was to screen crops for the most commonly isolated Fusarium species and to quantify DON and NIV to...

OBJECTIVES Dysbaric osteonecrosis (DON) is a complication of ineffective decompression following exposure to high-pressure environments. This study was designed to determine risk factors for the occurrence of DON in divers. METHODS Fifty-six male divers received skeletal examinations by radiography to assess the occurrence of DON. A questionnaire was used to obtain clinical and diving informa...

The trichothecene mycotoxin deoxynivalenol (DON) is commonly found as a natural contaminant in cereals such as wheat, barley, and corn, and exhibits various toxicological effects when present in animal feeds. The effects of DON at a nominal 2 mg/kg feed on immune responses of rainbow trout were investigated, including relative gene expression of important cytokines (TNF-α, IL-8, IL-1β, IL-10), ...

The mycotoxins deoxynivalenol (DON) and nivalenol (NIV), worldwide cereal contaminants, raise concerns for animal and human gut health, following contaminated food or feed ingestion. The impact of DON and NIV on intestinal mucosa was investigated after acute exposure, in vitro and in vivo. The histological changes induced by DON and NIV were analyzed after four-hour exposure on pig jejunum expl...

This study investigates the long-term effects of deoxynivalenol (DON) consumption on avian growth performance, on the proliferation, apoptosis, and DNA damage of spleen cells, and on intestinal integrity. Two hundred and eight 5-day-old black-feathered Taiwan country chickens were fed diets containing 0, 2, 5, and 10 mg/kg of DON for 16 weeks. Body weight gain of male birds in the 2 mg/kg group...