The 18S ribosomal DNA (rDNA) and cytochrome oxidase I region of mitochondrial DNA (mtDNA) were sequenced for 24 Xiphinema americanum-group populations sourced from a number of geographically disparate locations. Sequences were subjected to phylogenetic analysis and compared. 18S rDNA strongly suggested that only X. pachtaicum, X. simile (two populations) and a X. americanum s.l. population from...

The aggregation behavior of anionic Cobalt(II) 4,4′,4ʺ,4‴-tetrasulfonated phthalocyanine, [Co(TSPc)4-] was studied at its various concentrations and different ionic strengths using optical absorption and resonance light scattering (RLS) spectroscopies in 5 mM phosphate buffer, pH 7.0 at 25 °C. The results show no aggregation behavior at concentration range of 5.1 × 10-6-7....

Understanding DNA–ligand binding interactions requires ligand screening, crystallization, and structure determination. In order to obtain insights into the amyloid peptide precursor (APP) gene–Thioflavin T (ThT) interaction, single crystals of two DNA sequences 5′-GCCCACCACGGC-3′ (PDB 8ASK) d(CCGGGGTACCCCGG)2 8ASH) were grown in presence ThT or its analogue 2-((4-(dimethylamino)benzylidene)amin...

Mitotic exit in budding yeast is regulated by the proteins Cdc14, APC/C(Cdh1), and Plk1. In this issue, Bassermann and colleagues (2008) show that this network of proteins has been rewired in human cells to control the cell cycle in response to DNA damage.

Reactive oxygen metabolites can pro­ mote carcinogenesis by damaging DNA. vi­ tamin C is a redox chemical with antioxi­ dant and pro-oxidant properties that may produce radical species depending on the presence of various conditions. Nevertheless, evidence presented herein discourages the consideration of any mutagenic or carcino­ genic activity of vitamin C. In contrast, it substantiates a pro...