نتایج جستجو برای: dmr
تعداد نتایج: 925 فیلتر نتایج به سال:
Fluorescent and luminescent probes are essential to both in vitro molecular assays and in vivo imaging techniques, and have been extensively used to measure biological function. However, little is known about the biological activity, thus potential interferences with the assay results, of these probe molecules. Here we show that D-luciferin, one of the most widely used bioluminescence substrate...
Fourier analysis and power spectrum estimation of the cosmic microwave background anisotropy on an incompletely sampled sky developed by Górski (1994) has been applied to the high-latitude portion of the 4-year COBE DMR 31.5, 53 and 90 GHz sky maps. Likelihood analysis using newly constructed Galaxy cuts (extended beyond |b| = 20 deg to excise the known foreground emission) and simultaneously c...
A long-standing goal of theorists has been to constrain cosmological parameters that define the structure formation theory from cosmic microwave background (CMB) anisotropy experiments and large-scale structure (LSS) observations. The status and future promise of this enterprise is described. Current band-powers in -space are consistent with a DeltaT flat in frequency and broadly follow inflati...
The Prader-Willi/Angelman imprinted domain on human chromosome 15q11-q13 is regulated by an imprinting control center (IC) composed of a sequence around the SNRPN promoter (PWS-SRO) and a sequence located 35 kb upstream (AS-SRO). We have previously hypothesized that the primary imprint is established on AS-SRO, which then confers imprinting on PWS-SRO. Here we examine this hypothesis using a tr...
Sensitive and quantitative measurements of clinically relevant protein biomarkers, pathogens and cells in biological samples would be invaluable for disease diagnosis, monitoring of malignancy, and for evaluating therapy efficacy. Biosensing strategies using magnetic nanoparticles (MNPs) have recently received considerable attention, since they offer unique advantages over traditional detection...
Geometric characteristics of random fields are exploited to test the consistency of density perturbation model spectra with COBE data. These CMB maps are analyzed using the number of anisotropy hot spots and their boundary curvature. CMB maps which account for instrumental effects and sky coverage are Monte Carlo generated. These simulations show that a scale invariant HarrisonZeldovich primord...
Clinical trials show that tyrosine kinase inhibitor (TKI) treatment can be discontinued in selected patients with chronic myeloid leukaemia (CML). Although updated CML guidelines support such procedure clinical routine, data on TKI stopping outside are limited. In this retrospective study utilising the Swedish registry, we examined discontinuation a population-based setting. Out of 584 diagnose...
In the present investigation natural phenolic antioxidants were extracted from Jojoba seed waste. Samples of defatted jojoba meal (JSM), detoxified residue (DMR) and shell (JSH) subjected to extraction by using various solvents: 70/30 (vol/vol) ethanol/water, methanol/water 60/40 acetone/water. Total phenolics content (TPC) is measured according Folin-Ciocalteu method. In addition, solvent extr...
Subterranean mammals spend their lives in dark, unventilated environments that are rich in carbon dioxide and ammonia and low in oxygen. Many of these animals are also long-lived and exhibit reduced aging-associated diseases, such as neurodegenerative disorders and cancer. We sequenced the genome of the Damaraland mole rat (DMR, Fukomys damarensis) and improved the genome assembly of the naked ...
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