Diabetic retinopathy is the leading cause of blindness among individuals of working age in industrialized nations, with most of the vision loss resulting from diabetic macular edema (DME). The formation of DME depends on the action of several growth factors and inflammatory mediators, but vascular endothelial growth factor (VEGF) appears to be critical for breaking down the blood-retinal barrie...

The identity and reversibility of the elementary steps required for catalytic combustion of dimethyl ether (DME) on Pt clusters were determined by combining isotopic and kinetic analyses with density functional theory estimates of reaction energies and activation barriers to probe the lowest energy paths. Reaction rates are limited by C-H bond activation in DME molecules adsorbed on surfaces of...

The Stretched-FrOnt-Leg (SFOL) pulse is a high-accuracy distance measuring equipment (DME) developed to support alternative positioning and navigation for aircraft during global satellite system outages. To facilitate the use of SFOL pulse, it best legacy DMEs that are already deployed transmit rather than current Gaussian through software changes only. When attempting in DMEs, greatest challen...

Solvent-driven water extraction (SDWE) has promising applications in hypersaline brine desalination, including zero-liquid discharge processing for industrial wastewaters, and resource recovery, such as the of lithium rare earth elements from solution mining leachates. In this study, we develop a computational thermodynamic framework to analyze liquid–liquid brines using dimethyl ether (DME), a...

The Galileo E5a/E5b signals and the GPS L5 signal lie within the Aeronautical Radionavigation Services (ARNS) band. They suffer interference from the services in this frequency band, in particular, high power pulsed signals from Distance Measuring Equipment (DME) and Tactical Air Navigation (TACAN) systems. The pulsed interference degrades received Signal to Interference and Noise Ratio (SINR),...

The fluorinated phenoxide OC6F5 forms the stable Eu(II) and Eu(III) derivatives (DME)2Eu(mu-OC6F5)3Eu(mu-OC6F5)3Eu(DME)2 and (DME)2Eu(OC6F5)3, as well as the heterovalent product (DME)2Eu(mu-OC6F5)3Eu(DME)(OC6F5)2, in redox reactions of Eu with HOC6F5 or in proton-transfer reactions of HOC6F5 with Eu(SPh)2. The divalent complex crystallizes as a trimer with three bridging phenoxides bridging ea...

BACKGROUND AND OBJECTIVE The purpose of this study is to compare cancellation and no-show rates in patients with diabetic macular edema (DME) and exudative macular degeneration (wet AMD). PATIENTS AND METHODS An anonymous survey was sent to 1,726 retina specialists inquiring as to the number of appointments their patients with DME and wet AMD attended, cancelled, or did not show up for in 201...

The objective of this study was to establish the baseline retinal hemodynamic characteristics of stratified groups of diabetic patients at increasing risk for the development of diabetic macular edema (DME). Group 1 had 50 control subjects, group 2 had 56 diabetic patients without clinically visible retinopathy, group 3 had 54 diabetic patients with microaneurysms and/or hard exudates within tw...

Diabetic retinopathy (DR) and diabetic macular edema (DME) are leading causes of blindness in the working-age population of most developed countries. The increasing number of individuals with diabetes worldwide suggests that DR and DME will continue to be major contributors to vision loss and associated functional impairment for years to come. Early detection of retinopathy in individuals with ...

In the design of high performance VLSI systems, minimization of clock skew is an increasingly important objective. Additionally, wirelength of clock routing trees should be minimized in order to reduce system power requirements and deformation of the clock pulse at the synchronizing elements of the system. In this paper, we rst present the Deferred-Merge Embedding (DME) algorithm, which embeds ...