Chronic kidney disease (CKD) is frequently complicated with hyponatremia, probably because of fluid overload or diuretic usage. Hyponatremia in CKD population is associated with increased mortality, but the effect on renal outcome was unknown. We investigated whether hyponatremia is associated with fluid status and is a prognostic indicator for adverse outcomes in a CKD cohort of 4,766 patients...

s 40 venous capacitance within a few minutes before any with oedema is defined as a clinical state where the braking phenomenon occurs before the therapeutic measurable increase in urinary output can be seen [1,2]. This rapid haemodynamic improvement is goal is reached. thought to be due to the release of vasodilatory prostaglandins [3]. However, in a study in patients with severe oedema, i.v. ...

D ESPITE claims to the contrary,1-4 experience in this clinic over the past 6 years has found little difference in the antihypertensive, diuretic, or "potassium-sparing qualities" among the various thiazide diuretics including chlorthalidone. All these agents have also caused hyperglycemia and hyperuricemia. The only difference between chlorthalidone and the thiazide diuretics has been its long...

Purpose: We aimed to retrospectively compare the surgical and nonsurgical follow-up results of ureteropelvic junction obstruction without diuretic response. Methods: Twenty nine pediatric patients (10 Female (F), 19 Male (M); mean: 4.4 ± 3.96 years old, range: 0-15) without diuretic response were subject of this study. The diuretic renography, intravenous pyelography, voiding and ultrasonograph...

OBJECTIVE To examine the effect of concomitant intake of beta blockers with angiotensin converting enzyme (ACE) inhibitors, diuretics, or both on plasma renin concentrations in a population based sample (MONICA survey, Augsburg, Germany). SUBJECT AND METHODS 728 individuals were studied, of whom 171 were treated using monotherapy (ACE inhibitor (n = 21), diuretic (n = 10), or beta blocker (n ...

The combination of angiotensin receptor blockers (ARB) and a thiazide diuretic (hereafter, ARB/diuretic) is expected to improve patient adherence and increase the therapeutic effects because of the lower number of pills that require to be administered. In addition, an ARB/diuretic combination alleviates hypokalemia that frequently develops in patients receiving thiazide diuretics. In this study...

Diuretics are the agents which cause increase in excretion of urine. Diabetes mellitus (DM) is a multi-factorial disorder characterized by hyperglycemia resulting from an increased hepatic glucose production and diminished insulin secretion. The present study was undertaken to study the diuretic and anti-diabetic activity of esculin. Esculin was found to have potent diuretic activity in normal ...