One of the main obstacles faced by translational neuroscience is the development of animal models of psychiatric disorders. Behavioural pharmacology studies indicate that psychedelic drugs, such as lysergic acid diethylamide (LSD) and dissociative drugs, such as phencyclidine (PCP), induce in healthy human volunteers psychotic and cognitive symptoms that resemble some of those observed in schiz...

This article describes the development and validation of the Multidimensional Inventory of Dissociation (MID). The MID is a 218-item, self-administered, multiscale instrument that comprehensively assesses the phenomenological domain of pathological dissociation and diagnoses the dissociative disorders. The MID measures 14 major facets of pathological dissociation; it has 23 dissociation diagnos...

Background: Somatoform and dissociative disorder categories have emerged from a common root, there was no apparent anatomical physiological basis which had temporal relationship to precipitating event. Objectives: To evaluate compare of stressful life events the patients somatoform disorders disorders. Materials methods: This comparative cross-sectional study carried out in outpatient departmen...

BACKGROUND Sexual abuse and head injury are important risk factors of pseudoseizures, reported in about a third of patients. Clinical experience suggests that asthma is another possible risk factor. OBJECTIVES To determine the relative prevalence of asthma in patients with pseudoseizures. METHODS A retrospective record review was undertaken of reported asthma in 102 patients with pseudoseiz...

OBJECTIVE Smaller hippocampal volume has been reported in several stress-related psychiatric disorders, including posttraumatic stress disorder (PTSD), borderline personality disorder with early abuse, and depression with early abuse. Patients with borderline personality disorder and early abuse have also been found to have smaller amygdalar volume. The authors examined hippocampal and amygdala...