Exhaustive mineralization of pentachlorophenolate ion (PCP) in phosphate buffer was carried out using anodic contact glow discharge electrolysis (CGDE), in which plasma was sustained between the electrolyte and anode. During CGDE, PCP degraded smoothly. The amount of total organic carbon decreased significantly, indicating the eventual conversion of the carbon atoms of benzene nucleus to inorga...

Neutropenic dogs with systemic candidiasis were studied to establish quantitative relationships between tissue burdens of microorganisms and the kinetics of transfused granulocytes. Three groups of dogs rendered neutropenic by chemotherapy were evaluated. Group I consisted of 8 control dogs that were not challenged with Candida albicans; group II. 6 dogs challenged with 1 0#{176} C. albicans; g...

The protein toxin staphylococcal enterotoxin B (SEB) produces a clinical syndrome somewhat similar to that of gram-negative endotoxins. Our studies indicate a further similarity to endotoxin in that SEB is rapidly cleared from the plasma of monkeys. However, data reported herein show that an effective Thorotrast blockade of the reticuloendothelial system (RES) does not produce a significant cha...

Actinomycin D produces changes in the cell cycle kinetics of Chinese hamster (HA1) and mouse mammary tumor cells (EMT6) cultivated in vitro. There was a reduced rate of progression of the cells through S phase and a G;, arrest, the duration and degree of which were drug dose depend ent. The lethal effects of the drug on the two cell lines were comparable. At the molecular level. DMA single-stra...

the effects of different concentrations of cdcl2 and alcl3 on nh4+ and no2? oxidation in an aqueous system were investigated. alcl3 had no effect on nh4+ removal and its oxidation to no2?, whereas no2? disappearance was greatly enhanced by alcl3. in contrast, cdcl2 delayed removal of nh4+ and its subsequent oxidation to no2? and also decreased the rate of no2? disappearance. when compared to th...

One of the great mysteries of the nucleolus surrounds its disappearance during mitosis and subsequent reassembly at late mitosis. Here, the relative dynamics of nucleolar disassembly and reformation were dissected using quantitative 4D microscopy with fluorescent protein-tagged proteins in human stable cell lines. The data provide a novel insight into the fates of the three distinct nucleolar s...

The kinetics of neutrophilic granulocytes half disappearance time shortened to 2.3 hr. and monocytes were examined simulMoreover, the intravascular granulocyte dietaneously in a patient suffering from cyclic tribution changed in favor of the marginal neutropenia. During the remission phase of granulocyte pool. During the neutropenic the disease the observed kinetic data for phase, the intravasc...

Neutrophil kinetics were studied in seven patients with acute malaria. Six patients with Plasmodium v/vax had a mean neutrophil count of 1651 ± 282/ cu mm (range 360-2340); the neutrophil count in one patient with P. falciparum malaria was normal (4600/cu mm). In all of these patients, the numbers of circulating nonsegmented neutrophils were increased, neutrophil half-disappearance times were p...

Changes in concentration of reduced and oxidized low-M(r) thiols were measured in blood and plasma before and after the separation of blood cells. If centrifugation of blood was postponed, the reduced form of homocysteine in plasma increased with time at 22 degrees C; in contrast, the concentrations of other reduced thiols (cysteine, glutathione, and cysteinylglycine) decreased. In plasma the r...

Neutropenic dogs with systemic candidiasis were studied to establish quantitative relationships between tissue burdens of microorganisms and the kinetics of transfused granulocytes. Three groups of dogs rendered neutropenic by chemotherapy were evaluated. Group I consisted of 8 control dogs that were not challenged with Candida albicans; group II. 6 dogs challenged with 1 0#{176} C. albicans; g...