BACKGROUND The measurement of health benefits is a key issue in health economic evaluations. There is very scarce empirical literature exploring the differences of using quality-adjusted life years (QALYs) or disability-adjusted life years (DALYs) as benefit metrics and their potential impact in decision-making. METHODS Two previously published models delivering outputs in QALYs, were adapted...

Assessing the health situation in populations has traditionally been carried out on the basis of mortality data, and where available, on the prevalence and/or incidence of disease. A new approach to quantifying the burden of disease has been developed which simultaneously considers both premature death as well as the non-fatal health consequences of disease and injury. The burden of disease app...

A quantitative microbial risk assessment was applied to evaluate the microbial risks of the Accra Urban Water System (AUWS). The exposure assessment was based on the count of indicator organisms in waste water from open roadside drains and in water and sand samples from the beach. The predicted total disease burden generated in a representative catchment of the AUWS (Odaw Catchment) was 36,329 ...

Violence is an important public health challenge with substantial economic consequences for the affected individuals, families, and communities. Using data from the World Health Organization (WHO) and the World Bank, the economic value of disability-adjusted life years (DALYs) lost due to violence in 2002 was estimated for WHO Member States and presented as a percentage of gross domestic produc...

BACKGROUND To support public health policy, information on the burden of disease is essential. In recent years, the Disability-Adjusted Life Year (DALY) has emerged as the most important summary measure of public health. DALYs quantify the number of healthy life years lost due to morbidity and mortality, and thereby facilitate the comparison of the relative impact of diseases and risk factors a...

BACKGROUND In the context of an epidemiologic transition in South Africa, in which cardiovascular disease is increasing, little is known about the stroke burden, particularly morbidity in rural populations. Risk factors for stroke are high, with hypertension prevalence of more than 50%. Accurate, up-to-date information on disease burden is essential in planning health services for stroke manage...

BACKGROUND Occupational non-malignant respiratory disease arises from exposure of workers to airborne agents, mostly particulate or dusts. We describe the worldwide mortality and morbidity from asthma, chronic obstructive pulmonary disease (COPD), and pneumoconioses arising from these occupational exposure and focus on cases reported in the year 2000. METHODS The proportions of workers expose...

BACKGROUND The worldwide mortality and morbidity from lung cancer, leukemia, and malignant mesothelioma arising from occupational exposures to carcinogens are described. Cases reported in the year 2000 that resulted from relevant past and current exposures are assessed. METHODS The proportions of workers exposed to the carcinogens of interest, and their levels of exposure, were estimated usin...

BACKGROUND AND OBJECTIVE An important input to decision-making and health planning is a consistent and comparative description of the population health status. The purpose of this study was to describe the burden of disease in the Region of Valencia (Spain). MATERIAL AND METHODS Disability-adjusted life years (DALYs) were calculated and divided into years of life lost (YLLs) and years lived w...

Background: The global burden of diseases (GBD) neurological disorders is increasing worldwide. purpose this study to determine the between 1990 and 2019 in Asian regions. Methods: GBD updated every year, most recent version provides according age, gender, region from 2019. was totally separately evaluated as incidence, prevalence, death, disability-adjusted life-years (DALYs), years life l...