نتایج جستجو برای: direct sequencing

تعداد نتایج: 542795  

2010
Kelly Oliner Todd Juan Sid Suggs Michael Wolf Ildiko Sarosi Daniel J Freeman Tibor Gyuris Will Baron Andreas Bakker Alex Parker Scott D Patterson

BACKGROUND Activating mutations in the KRAS gene occur frequently in human tumors, including colorectal carcinomas; most mutations occur in codons 12 and 13. Mutations in KRAS have been associated with poor response to anti-epidermal growth factor receptor antibodies. Therefore, an accurate and readily available analysis of KRAS mutational status is needed. The aim of this study was to evaluate...

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