نتایج جستجو برای: direct mutagenesis

تعداد نتایج: 451037  

Journal: :Journal of Biological Chemistry 1988

Journal: :Genetics 2009
Rodrigo S Galhardo Robert Do Masami Yamada Errol C Friedberg P J Hastings Takehiko Nohmi Susan M Rosenberg

Stress-induced mutagenesis is a collection of mechanisms observed in bacterial, yeast, and human cells in which adverse conditions provoke mutagenesis, often under the control of stress responses. Control of mutagenesis by stress responses may accelerate evolution specifically when cells are maladapted to their environments, i.e., are stressed. It is therefore important to understand how stress...

2017
Eynat Dellus-Gur Yoav Ram Lilach Hadany

Stress-induced mutagenesis is a widely observed phenomenon. Theoretical models have shown that stress-induced mutagenesis can be favoured by natural selection due to the beneficial mutations it generates. These models, however, assumed an error-free regulation of mutation rate in response to stress. Here, we explore the effects of errors in the regulation of mutagenesis on the evolution of stre...

Journal: :Journal of Bacteriology 1959

Journal: :Journal of Computational Biology 2011

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